黄酮类木犀草素抑制粒细胞Fcγ依赖性呼吸爆发但不抑制成年小鼠新型类天疱疮模型皮肤水疱形成

资源简介

黄酮类木犀草素抑制粒细胞Fcγ依赖性呼吸爆发但不抑制成年小鼠新型类天疱疮模型皮肤水疱形成

【数据集背景】

本数据集源站标题为《The Flavonoid Luteolin Inhibits Fcγ-Dependent Respiratory Burst in Granulocytes, but Not Skin Blistering in a New Model of Pemphigoid in Adult Mice》。配套论文《The Flavonoid Luteolin Inhibits Fcγ-Dependent Respiratory Burst in Granulocytes, but Not Skin Blistering in a New Model of Pemphigoid in Adult Mice》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0031066。源站首次发布：2012-02-06。

【数据内容】

源站原始描述：Bullous pemphigoid is an autoimmune blistering skin disease associated with autoantibodies against the dermal-epidermal junction. Passive transfer of antibodies against BP180/collagen (C) XVII, a major hemidesmosomal pemphigoid antigen, into neonatal mice results in dermal-epidermal separation upon applying gentle pressure to their skin, but not in spontaneous skin blistering. In addition, this neonatal mouse model precludes treatment and observation of diseased animals beyond 2–3 days. Therefor…

【数据结构与技术规格】

文件数 3 个，合计 5.50 MB。Figure_S1.tif：image/tiff，4.85 MB。Figure_S2.tif：image/tiff，406.28 KB。Figure_S3.tif：image/tiff，252.29 KB。数据集 DOI：10.1371/journal.pone.0031066。

【主题与分类】

源站学科分类：Developmental Biology、Immunology。主题标签：flavonoid、luteolin、inhibits、respiratory、blistering、pemphigoid、mice。

【适用方向】

源站学科分类标注为 Developmental Biology、Immunology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/The_Flavonoid_Luteolin_Inhibits_Fc_Dependent_Respiratory_Burst_in_Granulocytes_but_Not_Skin_Blistering_in_a_New_Model_of_Pemphigoid_in_Adult_Mice/129085

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Oswald, Eva; Sesarman, Alina; Franzke, Claus-Werner; Wölfle, Ute; Bruckner-Tuderman, Leena; Jakob, Thilo; et al. (2016). The Flavonoid Luteolin Inhibits Fcγ-Dependent Respiratory Burst in Granulocytes, but Not Skin Blistering in a New Model of Pemphigoid in Adult Mice. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。