人类嗜酸性粒细胞在大疱性类天疱疮中表达高亲和力IgE受体FcεRI

资源简介

人类嗜酸性粒细胞在大疱性类天疱疮中表达高亲和力IgE受体FcεRI

【数据集背景】

本数据集源站标题为《Human Eosinophils Express the High Affinity IgE Receptor, FcεRI, in Bullous Pemphigoid》。配套论文《Human Eosinophils Express the High Affinity IgE Receptor, FcεRI, in Bullous Pemphigoid》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0107725。源站首次发布：2014-09-25。

【数据内容】

源站原始描述：Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP180 (type XVII collagen). Patient sera and tissues typically have IgG and IgE autoantibodies and elevated eosinophil numbers. Although the pathogenicity of the IgE autoantibodies is established in BP, their contribution to the disease process is not well understood. Our aims were two-fold: 1) To establish the clinical relationships between total and BP180-specific IgE, eosinophilia and other marker…

【数据结构与技术规格】

文件数 2 个，合计 7.51 MB。Movie_S1.avi：video/x-msvideo，4.99 MB。Movie_S2.avi：video/x-msvideo，2.53 MB。数据集 DOI：10.1371/journal.pone.0107725。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：BP 180 IgE levels、trimeric receptor form、IgE autoantibodies、proximity ligation assay、Bullous Pemphigoid Bullous pemphigoid、Human Eosinophils Express、eosinophil count、BP 180 IgE、BP 180 IgG、BP 230 IgG。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Human_Eosinophils_Express_the_High_Affinity_IgE_Receptor_Fc_949_RI_in_Bullous_Pemphigoid_/1182630

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：N. Messingham, Kelly; M. Holahan, Heather; S. Frydman, Alexandra; Fullenkamp, Colleen; Srikantha, Rupasree; A. Fairley, Janet (2016). Human Eosinophils Express the High Affinity IgE Receptor, FcεRI, in Bullous Pemphigoid. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。