表1_胃酸分泌抑制剂对呼吸机相关性肺炎的影响

包含胃酸分泌抑制剂(PPIs和H2RAs)与呼吸机相关性肺炎及院内死亡率关联分析的表格数据集,基于MIMIC-IV数据库。

NIAID Data Ecosystem
浏览 13
表格ventilator-associated pneumoniamortalityproton pump inhibitorhistamine 2 receptor antagonistgastric acid secretion inhibitors
Table1_Effects of Gastric Acid Secretion Inhibitors for Ventilator-Associated Pneumonia.XLSX

基本信息

模态
表格
大小
0.000009412 GB
许可
CC BY 4.0
创建/更新时间
2026-10-07
版本
v1

资源简介

表1_胃酸分泌抑制剂对呼吸机相关性肺炎的影响

【一句话概览】

本数据集是 figshare 公开的结构化表格数据集,收录 1 个文件、合计 9.41 KB,主题涵盖 ventilator-associated pneumonia、mortality、proton pump inhibitor、histamine 2 receptor antagonist、gastric acid secretion inhibitors,可用于统计建模、特征工程与队列分析,CC BY 4.0 许可开放获取。

【数据集背景】

本数据集源站标题为《Table1_Effects of Gastric Acid Secretion Inhibitors for Ventilator-Associated Pneumonia.XLSX》。配套论文《Guidelines for the Management of Adults with Hospital-acquired, Ventilator-associated, and Healthcare-associated Pneumonia》发表于 American Journal of Respiratory and Critical Care Medicine(2005),DOI:10.1164/rccm.200405-644ST。源站首次发布:2022-05-05。

【数据内容】

源站原始描述:Objective: This study analyzed the association of gastric acid secretion inhibitors (GASIs) [including proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs)] with the occurrence of ventilator-associated pneumonia (VAP) and in-hospital mortality in patients who received invasive mechanical ventilation (IMV). Method: Patients who received IMV and used GASI were included based on records in the MIMIC-IV database. The relationships of GASIs with VAP and the in-hospital mortality…

中文译文(机器翻译,仅供快速理解,请以原文为准):目的:本研究分析了胃酸分泌抑制剂(GASIs)[包括质子泵抑制剂(PPIs)和组胺2受体拮抗剂(H2RAs)]与接受有创机械通气(IMV)患者呼吸机相关性肺炎(VAP)发生及院内死亡率的关系。 方法:基于MIMIC-IV数据库记录,纳入接受IMV并使用GASI的患者。采用单因素和多因素logistic回归分析确定GASIs与VAP及院内死亡率的关系。同时,进一步分析GASIs在某些人群亚组中的效应。 结果:共纳入18,669例患者,其中仅使用H2RAs者9191例,仅使用PPIs者6921例,联合使用两种药物者2557例。应用logistic回归的单因素和多因素模型显示,与H2RAs相比,PPIs对VAP发生率无显著影响,而H2RAs与PPIs联合使用是VAP的危险因素。与H2RAs相比,单因素logistic回归显示,PPIs及联合使用两种药物均为院内死亡率的危险因素,但多因素logistic回归显示它们与院内死亡率无显著关联。在亚组分析中,年龄、PCO2、心肌梗死、充血性心力衰竭的不同亚组间存在交互作用(交互作用P值 结论:与H2RAs相比,PPIs与VAP或院内死亡率均无显著关联;H2RAs与PPIs联合使用是VAP的危险因素,但与院内死亡率无显著关联。

【数据结构与技术规格】

文件数 1 个,合计 9.41 KB。Table1_Effects of Gastric Acid Secretion Inhibitors for Ventilator-Associated Pneumonia.XLSX:application/vnd.openxmlformats-officedocument.spreadsheetml.sheet,9.41 KB。数据集 DOI:10.3389/fphar.2022.898422.s001。

【主题与分类】

源站学科分类:Basic Pharmacology、Clinical Pharmacology and Therapeutics、Clinical Pharmacy and Pharmacy Practice、Pharmaceutical Sciences、Pharmacogenomics、Pharmacology。主题标签:ventilator-associated pneumonia、mortality、proton pump inhibitor、histamine 2 receptor antagonist、gastric acid secretion inhibitors。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面:https://frontiersin.figshare.com/articles/dataset/Table1_Effects_of_Gastric_Acid_Secretion_Inhibitors_for_Ventilator-Associated_Pneumonia_XLSX/19710106

使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。

规范引用:Li, Fang; Liu, Hui; Zhang, Luming; Huang, Xiaxuan; Liu, Yu; Li, Boen; et al. (2022). Table1_Effects of Gastric Acid Secretion Inhibitors for Ventilator-Associated Pneumonia.XLSX. Frontiers. Dataset

【使用注意】

· 源站最后修改于 2023-06-03,引用时请注意版本时效。

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下载信息

注册下载

需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。

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公开下载

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当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。

使用方式

数据集获取(Figshare)

命令行下载

curl -L -o "Table1_Effects of Gastric Acid Secretion Inhibitors for Ventilator-Associated Pneumonia.XLSX" "https://ndownloader.figshare.com/files/35010064"

文件清单

  • Table1_Effects of Gastric Acid Secretion Inhibitors for Ventilator-Associated Pneumonia.XLSX(9.41 KB)

文件总体积 9.41 KB(源站 API 实测)。

数据加载示例(图像类)

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Objective: This study analyzed the association of gastric acid secretion inhibitors (GASIs) [including proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs)] with the occurrence of ventilator-associated pneumonia (VAP) and in-hospital mortality in patients who received invasive mechanical ventilation (IMV).
Method: Patients who received IMV and used GASI were included based on records in the MIMIC-IV database. The relationships of GASIs with VAP and the in-hospital mortality were determined using univariate and multivariate logistic regression analyses. Also, the effects of GASIs in some subgroups of the population were further analyzed.
Results: A total of 18,669 patients were enrolled, including 9191 patients on H2RAs only, 6921 patients on PPIs only, and 2557 were on a combination of the two drugs. Applying logistic regression to the univariate and multivariate models revealed that compared with H2RAs, PPIs had no significant effect on the incidence of VAP, and the combination of H2RAs and PPIs was a risk factor for VAP. Compared with H2RAs, univariate logistic regression revealed that, PPIs and combine the two drugs were both risk factors for in-hospital mortality, but multivariate logistic regression showed that they were not significantly associated with in-hospital mortality. In subgroup analysis, there were interaction in different subgroups of age, PCO2, myocardial infarct, congestive heart failure (P for interactionConclusion: Compared with H2RAs, PPIs did not have a significant association with either VAP or in-hospital mortality; the combination of H2RAs and PPIs was risk factor for VAP, but did not have a significantly associated with in-hospital mortality.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.3389/fphar.2022.898422.s001(source: https://frontiersin.figshare.com/articles/dataset/Table1_Effects_of_Gastric_Acid_Secretion_Inhibitors_for_Ventilator-Associated_Pneumonia_XLSX/19710106)。

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