MicroRNA-941在多形核粒细胞中的表达与肉芽肿性多血管炎无关

资源简介

MicroRNA-941在多形核粒细胞中的表达与肉芽肿性多血管炎无关

【数据集背景】

本数据集源站标题为《MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis》。配套论文《MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis》发表于 PLOS ONE（2016），DOI：10.1371/journal.pone.0164985。源站首次发布：2016-10-18。

【数据内容】

源站原始描述：Jumonji Domain-Containing Protein 3 (JMJD3)/lysine demethylase 6B (KDM6B) is an epigenetic modulator that removes repressive histone marks on genes. Expression of KDM6B mRNA is elevated in leukocytes from patients with ANCA-associated vasculitis (AAV) and has been suggested to be the reason for higher proteinase 3 (PR3) mRNA expression in these cells due to derepression of PRTN3 gene transcription. MicroRNA-941 (miR-941) has been shown to target KDM6B mRNA and inhibit JMJD3 production. We theref…

【数据结构与技术规格】

文件数 3 个，合计 27.10 MB。数据集 DOI：10.1371/journal.pone.0164985。

【主题与分类】

源站学科分类：Biochemistry、Cell Biology、Genetics、Molecular Biology、Physiology、Chemical Sciences not elsewhere classified。主题标签：target KDM 6B mRNA、GPA patients、KDM 6B mRNAs、miR -941 expression levels、PRTN 3 mRNA、PRTN 3 gene transcription、MicroRNA -941 Expression、FCGR、JMJD 3 levels、Polyangiitis Jumonji Domain-Containing Protein 3。

【适用方向】

源站学科分类标注为 Biochemistry、Cell Biology、Genetics、Molecular Biology、Physiology、Chemical Sciences not elsewhere classified。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/MicroRNA-941_Expression_in_Polymorphonuclear_Granulocytes_Is_Not_Related_to_Granulomatosis_with_Polyangiitis/4041981

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Svendsen, Jesper Brink; Baslund, Bo; Cramer, Elisabeth Præstekjær; Rapin, Nicolas; Borregaard, Niels; Cowland, Jack Bernard (2016). MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。