肺囊虫肺炎诊断选项的成本效益分析

数据集获取（Figshare）

• 源站标题：Cost-Effectiveness Analysis of Diagnostic Options for <em>Pneumocystis</em> Pneumonia (PCP)
• DOI：10.1371/journal.pone.0023158
• 发布日期：2011-08-15
• 文件数：5 个
• 文件总体积：363.52 KB
• 源站页面：https://plos.figshare.com/articles/dataset/Cost_Effectiveness_Analysis_of_Diagnostic_Options_for_Pneumocystis_Pneumonia_PCP_/134263

命令行下载

curl -L -o "Table_S1.doc" "https://ndownloader.figshare.com/files/375941"
curl -L -o "Table_S2.doc" "https://ndownloader.figshare.com/files/375983"
curl -L -o "Table_S3.doc" "https://ndownloader.figshare.com/files/376019"
curl -L -o "Table_S4.doc" "https://ndownloader.figshare.com/files/376048"
curl -L -o "Appendix_S1.doc" "https://ndownloader.figshare.com/files/376094"

文件清单

• Table_S1.doc（80.38 KB）
• Table_S2.doc（103.94 KB）
• Table_S3.doc（39.42 KB）
• Table_S4.doc（96.26 KB）
• Appendix_S1.doc（43.52 KB）

文件总体积 363.52 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
Diagnosis of Pneumocystis jirovecii pneumonia (PCP) is challenging, particularly in developing countries. Highly sensitive diagnostic methods are costly, while less expensive methods often lack sensitivity or specificity. Cost-effectiveness comparisons of the various diagnostic options have not been presented.
Methods and Findings
We compared cost-effectiveness, as measured by cost per life-years gained and proportion of patients successfully diagnosed and treated, of 33 PCP diagnostic options, involving combinations of specimen collection methods [oral washes, induced and expectorated sputum, and bronchoalveolar lavage (BAL)] and laboratory diagnostic procedures [various staining procedures or polymerase chain reactions (PCR)], or clinical diagnosis with chest x-ray alone. Our analyses were conducted from the perspective of the government payer among ambulatory, HIV-infected patients with symptoms of pneumonia presenting to HIV clinics and hospitals in South Africa. Costing data were obtained from the National Institutes of Communicable Diseases in South Africa. At 50% disease prevalence, diagnostic procedures involving expectorated sputum with any PCR method, or induced sputum with nested or real-time PCR, were all highly cost-effective, successfully treating 77–90% of patients at $26–51 per life-year gained. Procedures using BAL specimens were significantly more expensive without added benefit, successfully treating 68–90% of patients at costs of $189–232 per life-year gained. A relatively cost-effective diagnostic procedure that did not require PCR was Toluidine Blue O staining of induced sputum ($25 per life-year gained, successfully treating 68% of patients). Diagnosis using chest x-rays alone resulted in successful treatment of 77% of patients, though cost-effectiveness was reduced ($109 per life-year gained) compared with several molecular diagnostic options.
Conclusions
For diagnosis of PCP, use of PCR technologies, when combined with less-invasive patient specimens such as expectorated or induced sputum, represent more cost-effective options than any diagnostic procedure using BAL, or chest x-ray alone.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0023158（source: https://plos.figshare.com/articles/dataset/Cost_Effectiveness_Analysis_of_Diagnostic_Options_for_Pneumocystis_Pneumonia_PCP_/134263）。