自发性高血压大鼠颈动脉体ATP传递加剧与球细胞增殖相关

资源简介

自发性高血压大鼠颈动脉体ATP传递加剧与球细胞增殖相关

【数据集背景】

本数据集源站标题为《Exacerbated ATP transmission in the carotid body is linked to glomus cell expansion in spontaneously hypertensive rats》。源站首次发布：2026-04-08。

【数据内容】

源站原始描述：ATP acting on P2X3 receptors contributes to carotid body (CB) hyperexcitability in spontaneously hypertensive rats (SHRs). We investigated whether this reflects altered ATP release and/or impaired ATP metabolism. Using in vitro CB preparations, we quantified ATP release in Wistar and SHR rats (n = 10 each) and found significantly greater ATP release in SHRs (P = 0.00062). Intracellular ATP depletion in dissociated glomus cells was similar between strains (n = 4 each). Morphometric analysis revea…

【数据结构与技术规格】

文件数 1 个，合计 117.62 KB。Data availability.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，117.62 KB。数据集 DOI：10.17608/k6.auckland.25106468.v9。

【主题与分类】

源站学科分类：Systems physiology、Cell physiology、Medical physiology not elsewhere classified。主题标签：carotid body chemoreceptors、ATP、P2X3 receptors、Hypertension。

【适用方向】

源站学科分类标注为 Systems physiology、Cell physiology、Medical physiology not elsewhere classified。

【获取与许可】

源站页面：https://auckland.figshare.com/articles/dataset/_b_Identifying_ATP_evoked_responses_from_the_carotid_body_in_spontaneously_hypertensive_rats_b_/25106468

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Felippe, Igor (2024). Exacerbated ATP transmission in the carotid body is linked to glomus cell expansion in spontaneously hypertensive rats. The University of Auckland. Dataset