物理限制改变肉瘤细胞周期进程与分裂

资源简介

物理限制改变肉瘤细胞周期进程与分裂

【数据集背景】

本数据集源站标题为《Physical confinement alters sarcoma cell cycle progression and division》。配套论文《Physical confinement alters sarcoma cell cycle progression and division》发表于 Cell Cycle（2018），DOI：10.1080/15384101.2018.1533776。项目资助方：This work was supported by the Burroughs Wellcome Fund.。源站首次发布：2019-01-02。

【数据内容】

源站原始描述：Tumor cells experience physical confinement on one or multiple axes, both in the primary tumor and at multiple stages during metastasis. Recent work has shown that confinement in a 3D spheroid alters nucleus geometry and delays cell division, and that vertical confinement impairs mitotic spindle rounding, resulting in abnormal division events. Meanwhile, the effects of bi-axial confinement on cell cycle progression has received little attention. Given the critical role of nuclear shape and mecha…

【数据结构与技术规格】

文件数 5 个，合计 3.32 MB。kccy_a_1533776_sm0767.avi：video/x-msvideo，176.01 KB。kccy_a_1533776_sm0755.avi：video/x-msvideo，153.17 KB。kccy_a_1533776_sm0754.avi：video/x-msvideo，404.17 KB。数据集 DOI：10.6084/m9.figshare.7338893.v2。

【主题与分类】

源站学科分类：Biophysics、Cell Biology、Genetics、Physiology、Biotechnology、Biological Sciences not elsewhere classified。主题标签：Mechanobiology、microchannels、cell shape、nucleus、cell migration。

【适用方向】

源站学科分类标注为 Biophysics、Cell Biology、Genetics、Physiology、Biotechnology、Biological Sciences not elsewhere classified。

【获取与许可】

源站页面：https://tandf.figshare.com/articles/dataset/Physical_confinement_alters_sarcoma_cell_cycle_progression_and_division/7338893

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Physical confinement alters sarcoma cell cycle progression and division. Taylor & Francis. Moriarty, Rebecca A.; M. Stroka, Kimberly

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。