前列腺癌PD-1/PD-L1免疫治疗综述数据表

前列腺癌PD-1/PD-L1免疫治疗综述中的表格数据,汇总临床研究信息。

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表格prostate cancerPD-1/PD-L1immune microenvironmentimmunotherapycombined therapy
Table 1_Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.xlsx

基本信息

模态
表格
大小
0.00002742 GB
许可
CC BY 4.0
创建/更新时间
2026-10-08
版本
v1

资源简介

前列腺癌PD-1/PD-L1免疫治疗综述数据表

【一句话概览】

本数据集是 figshare 公开的结构化表格数据集,收录 1 个文件、合计 27.42 KB,主题涵盖 prostate cancer、PD-1/PD-L1、immune microenvironment、immunotherapy、combined therapy,可用于统计建模、特征工程与队列分析,CC BY 4.0 许可开放获取。

【数据集背景】

本数据集源站标题为《Table 1_Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.xlsx》。配套论文《Progression in immunotherapy for advanced prostate cancer》发表于 Frontiers in Oncology(2023),DOI:10.3389/fonc.2023.1126752。源站首次发布:2026-01-31。

【数据内容】

源站原始描述:Prostate cancer (PCa), the most prevalent malignancy among male genitourinary cancers, is distinguished by its immunologically ”cold” phenotype with persistently high incidence and mortality. Radical prostatectomy and radiotherapy represent the current standard of care for localized prostate cancer. However, recurrence or progression occurs frequently, and advanced or metastatic disease is common at initial presentation. Recent progress in cancer immunotherapy reveals that modulation of immune r…

中文译文(机器翻译,仅供快速理解,请以原文为准):前列腺癌(PCa)是男性泌尿生殖系统癌症中最常见的恶性肿瘤,以其免疫“冷”表型为特征,且发病率和死亡率持续居高。根治性前列腺切除术和放疗是局限性前列腺癌的当前标准治疗。然而,复发或进展频繁发生,且初诊时晚期或转移性疾病很常见。近期癌症免疫治疗的进展表明,调节免疫反应是增强抗肿瘤活性的有效策略。程序性细胞死亡蛋白1和程序性细胞死亡配体1(PD-1/PD-L1)抑制剂可恢复T细胞功能并重塑肿瘤免疫微环境,已在黑色素瘤、淋巴瘤和非小细胞肺癌中取得临床成功。尽管其作为单药治疗PCa的疗效仍然有限,且缺乏最佳患者选择标准,但新出现的证据表明,联合免疫治疗方案可能带来具有临床意义的获益。本综述批判性评估了当前涉及PD-1/PD-L1抑制剂治疗前列腺癌的临床试验结果,并概述了未来研究的优先方向。

【数据结构与技术规格】

文件数 1 个,合计 27.42 KB。Table 1_Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.xlsx:application/vnd.openxmlformats-officedocument.spreadsheetml.sheet,27.42 KB。数据集 DOI:10.3389/fimmu.2025.1664587.s001。

【主题与分类】

源站学科分类:Genetic Immunology。主题标签:prostate cancer、PD-1/PD-L1、immune microenvironment、immunotherapy、combined therapy。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面:https://frontiersin.figshare.com/articles/dataset/Table_1_Advances_in_the_application_of_PD-1_PD-L1_immunotherapy_for_prostate_cancer_a_review_xlsx/31216438

使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。

规范引用:Hu, Guangqiang; Li, Zeng; Chen, Yongji; Liao, Hong; Zhou, Shukui (2026). Table 1_Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.xlsx. Frontiers. Dataset

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从合规授权、采集治理、专业标注到数据集交付,我们提供全链路闭环服务,让高质量临床数据即拿即用。

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下载信息

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需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。

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使用方式

数据集获取(Figshare)

命令行下载

curl -L -o "Table 1_Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.xlsx" "https://ndownloader.figshare.com/files/61528981"

文件清单

  • Table 1_Advances in the application of PD-1/PD-L1 immunotherapy for prostate cancer: a review.xlsx(27.42 KB)

文件总体积 27.42 KB(源站 API 实测)。

数据说明

Prostate cancer (PCa), the most prevalent malignancy among male genitourinary cancers, is distinguished by its immunologically ”cold” phenotype with persistently high incidence and mortality. Radical prostatectomy and radiotherapy represent the current standard of care for localized prostate cancer. However, recurrence or progression occurs frequently, and advanced or metastatic disease is common at initial presentation. Recent progress in cancer immunotherapy reveals that modulation of immune responses represents an effective strategy for enhancing antitumor activity. Programmed Cell Death Protein 1 and Programmed Cell Death Ligand 1 (PD-1/PD-L1) inhibitors, which restore T-cell function and remodel the tumor immune microenvironment, have achieved clinical success in melanoma, lymphoma and non-small-cell lung cancer. Although their efficacy as monotherapy in PCa remains limited and optimal patient selection criteria are lacking, emerging evidence suggests that combination immunotherapy regimens may offer clinically significant benefits. This review critically evaluates current clinical trial outcomes involving PD-1/PD-L1 inhibitors for prostate cancer and outlines priority directions for future investigation.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.3389/fimmu.2025.1664587.s001(source: https://frontiersin.figshare.com/articles/dataset/Table_1_Advances_in_the_application_of_PD-1_PD-L1_immunotherapy_for_prostate_cancer_a_review_xlsx/31216438)。

数据缺失?

依托陕西、四川两大基地,我们与超过十家三甲医院建立直接合作关系,覆盖合规授权、采集治理、专业标注、数据交付的全流程,为AI医疗团队提供即拿即用的高质量临床数据。

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