儿童质子放疗后严重晚期并发症数据集：2008-2019年完整瑞典队列

数据集获取（Figshare）

• 源站标题：Complications after proton radiotherapy in children, focusing on severe late complications. A complete Swedish cohort 2008–2019
• DOI：10.6084/m9.figshare.24213022.v1
• 发布日期：2023-09-28
• 文件数：3 个
• 文件总体积：74.34 KB
• 源站页面：https://tandf.figshare.com/articles/dataset/Complications_after_proton_radiotherapy_in_children_focusing_on_severe_late_complications_A_complete_Swedish_cohort_2008_2019/24213022

命令行下载

curl -L -o "sonc_2023_0214_File006Table1S.docx" "https://ndownloader.figshare.com/files/42498232"
curl -L -o "sonc_2023_0214_File007Table2S.docx" "https://ndownloader.figshare.com/files/42498235"
curl -L -o "sonc_2023_0214_File008EQUATOR.docx" "https://ndownloader.figshare.com/files/42498238"

文件清单

• sonc_2023_0214_File006Table1S.docx（21.91 KB）
• sonc_2023_0214_File007Table2S.docx（26.29 KB）
• sonc_2023_0214_File008EQUATOR.docx（26.14 KB）

文件总体积 74.34 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Proton radiotherapy (RT) is an attractive tool to deliver local therapy with minimal dose to uninvolved tissue, however, not suitable for all patients. The aim was to explore complications, especially severe late complications (grades 3–4), following proton RT delivered to a complete Swedish cohort of paediatric patients aged Data was downloaded from a national registry. Complications with a possible causation with RT are reported. Proton treatments until July 2015 was performed with a fixed horizontal 172 MeV beam (The Svedberg Laboratory (TSL), Uppsala) in a sitting position and thereafter with gantry-based pencil-beam scanning technique (Skandion Clinic, Uppsala) in a supine position.
219 courses of proton RT (77 at TSL and 142 at Skandion) were delivered to 212 patients (mean age 9.2 years) with various tumour types (CNS tumours 58%, sarcomas 26%, germ cell tumours 7%). Twenty-five patients had severe acute complications (skin, mucous membrane, pharynx/oesophagus, larynx, upper gastrointestinal canal, lower gastrointestinal canal, eyes, ears). Fifteen patients had severe late complications; with increased proportion over time: 4% at 1-year follow-up (FU), 5% at 3-year, 11% at 5-year. Organs affected were skin (1 patient), subcutaneous tissue (4), salivary glands (1), upper GI (1), bone (7), joints (2), CNS (2), PNS (1), eyes (1) and ears (5). Twenty-one of the 28 patients with 10-year FU had at least one late complication grades 1–4 and fourteen of them had more than one (2–5 each).
The most important result of our study is the relatively low proportion of severe late complications, comparable with other proton studies on various tumours. Furthermore, the numbers of late complications are lower than our own data set on a mixed population of photon and proton treated paediatric patients, assuring the safety of using proton therapy also in the clinical practice.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.24213022.v1（source: https://tandf.figshare.com/articles/dataset/Complications_after_proton_radiotherapy_in_children_focusing_on_severe_late_complications_A_complete_Swedish_cohort_2008_2019/24213022）。