医生对晚期卵巢癌患者遗传生物标志物检测的知识、使用和认知：一项国际医生调查

数据集获取（Figshare）

• 源站标题：Physician knowledge, use, and perceptions of genetic biomarker testing for the management of patients with newly diagnosed advanced ovarian cancer: an international physician survey
• DOI：10.6084/m9.figshare.28218057.v2
• 发布日期：2025-02-07
• 文件数：8 个
• 文件总体积：577.31 KB
• 源站页面：https://tandf.figshare.com/articles/dataset/Physician_knowledge_use_and_perceptions_of_genetic_biomarker_testing_for_the_management_of_patients_with_newly_diagnosed_advanced_ovarian_cancer_an_international_physician_survey/28218057

命令行下载

curl -L -o "ifon_a_2449782_sm9877.docx" "https://ndownloader.figshare.com/files/52190154"
curl -L -o "ifon_a_2449782_sm9876.docx" "https://ndownloader.figshare.com/files/52190157"
curl -L -o "ifon_a_2449782_sm9872.docx" "https://ndownloader.figshare.com/files/52190160"
curl -L -o "ifon_a_2449782_sm9871.docx" "https://ndownloader.figshare.com/files/52190163"
curl -L -o "ifon_a_2449782_sm9870.docx" "https://ndownloader.figshare.com/files/52190166"
curl -L -o "ifon_a_2449782_sm9869.docx" "https://ndownloader.figshare.com/files/52190169"
curl -L -o "ifon_a_2449782_sm9866.pdf" "https://ndownloader.figshare.com/files/52190172"
curl -L -o "ifon_a_2449782_sm9858.docx" "https://ndownloader.figshare.com/files/52190175"

文件清单

• ifon_a_2449782_sm9877.docx（18.87 KB）
• ifon_a_2449782_sm9876.docx（17.88 KB）
• ifon_a_2449782_sm9872.docx（24.54 KB）
• ifon_a_2449782_sm9871.docx（32.73 KB）
• ifon_a_2449782_sm9870.docx（18.88 KB）
• ifon_a_2449782_sm9869.docx（17.07 KB）
• ifon_a_2449782_sm9866.pdf（427.81 KB）
• ifon_a_2449782_sm9858.docx（19.52 KB）

文件总体积 577.31 KB（源站 API 实测）。

数据说明

To explore physician-reported knowledge, use, and perceptions of genetic testing for advanced ovarian cancer management.
Gynecology/oncology specialists (n = 390) in the US, Europe, Canada, Japan, and Australia completed an online survey spanning March 2021 to April 2022.
Physician-reported breast cancer gene mutation (BRCAm) testing rates increased over the 2 years before the survey; most patients underwent testing in the preceding 6 months. Homologous recombination deficiency (HRD) genomic instability testing rates and physicians’ confidence interpreting results remained relatively low. Genetic testing was driven by the associated treatment implications of the findings. Poor performance status, inadequate tissue, and patients’ willingness to undergo testing were reported barriers to testing.
Findings indicate that there is a need to improve both access to and information about HRD testing.
Why did we perform this research?
Testing for breast cancer gene mutations (BRCAm) is strongly recommended to guide treatment decisions for patients with ovarian cancer (OC), with screening for homologous recombination deficiency (HRD) genomic instability (when cells cannot accurately repair breaks in DNA strands) also recommended. However, not all eligible women are tested, indicating that a greater understanding of physicians’ testing practices is needed.
What did we do?
Physicians (n = 390) in the US, Europe, Canada, Japan, and Australia completed an online survey that evaluated their knowledge, use, and perceptions of genetic testing for advanced OC management.
What were the results?
Across all countries, physicians reported increasing BRCAm testing rates over the 2 years before the survey, with most patients with advanced OC now receiving these tests. HRD testing rates were relatively low, and few physicians reported complete confidence in interpreting these test results. Physicians most commonly reported that genetic testing was conducted because the results could guide treatment decisions. The main reasons for not conducting tests were patients being too unwell, tissue samples being inadequate, or patients being unwilling to undergo testing. Across countries,

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.28218057.v2（source: https://tandf.figshare.com/articles/dataset/Physician_knowledge_use_and_perceptions_of_genetic_biomarker_testing_for_the_management_of_patients_with_newly_diagnosed_advanced_ovarian_cancer_an_international_physician_survey/28218057）。