整合蛋白质组分析与药物筛选识别MET通路治疗恶性外周神经鞘瘤潜力的数据集

资源简介

整合蛋白质组分析与药物筛选识别MET通路治疗恶性外周神经鞘瘤潜力的数据集

【数据集背景】

本数据集源站标题为《Integrating analysis of proteome profile and drug screening identifies therapeutic potential of MET pathway for the treatment of malignant peripheral nerve sheath tumor》。配套论文《Integrating analysis of proteome profile and drug screening identifies therapeutic potential of MET pathway for the treatment of malignant peripheral nerve sheath tumor》发表于 Expert Review of Proteomics（2023），DOI：10.1080/14789450.2023.2218035。项目资助方：This research was funded by the Japan Agency for Medical Research and Development (grant number 20ck0106537h0002)。源站首次发布：2023-05-29。

【数据内容】

源站原始描述：Malignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with a poor prognosis that requires novel therapeutic agents. Proteome information is useful for identifying new therapeutic candidates because it directly reflects the biological phenotype. Additionally, in vitro drug screening is an effective tool to identify candidate drugs for common cancers. Hence, we attempted to identify novel therapeutic candidates for MPNST by integrating proteomic analysis and drug screening. We p…

【数据结构与技术规格】

文件数 6 个，合计 341.67 KB。Supplementary Figure 1 IC50.tif：image/tiff，203.54 KB。Supplementary Table 1 Data of individual cases_revised.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，13.86 KB。Supplementary Table 2 Drug list_revised.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，25.40 KB。数据集 DOI：10.6084/m9.figshare.23257163.v1。

【主题与分类】

源站学科分类：Biochemistry、Medicine、Genetics、Molecular Biology、Neuroscience、Pharmacology。主题标签：Drug screening、emPAI、Malignant peripheral nerve sheath tumor、Mass spectrometry、MET pathway、Patient-derived cell line。

【适用方向】

源站学科分类标注为 Biochemistry、Medicine、Genetics、Molecular Biology、Neuroscience、Pharmacology。

【获取与许可】

源站页面：https://tandf.figshare.com/articles/dataset/Integrating_analysis_of_proteome_profile_and_drug_screening_identifies_therapeutic_potential_of_MET_pathway_for_the_treatment_of_malignant_peripheral_nerve_sheath_tumor/23257163

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Integrating analysis of proteome profile and drug screening identifies therapeutic potential of MET pathway for the treatment of malignant peripheral nerve sheath tumor. Taylor & Francis. Tsuchiya, Ryuto; Yoshimatsu, Yuki; Noguchi, Rei; Sin, Yooksil; Ono, Takuya; Akiyama, Taro; et al

【使用注意】

· 源站最后修改于 2023-06-29，引用时请注意版本时效。