培美曲塞和铂类药物在间皮瘤长期幸存者中的分子耐药指纹图谱

资源简介

培美曲塞和铂类药物在间皮瘤长期幸存者中的分子耐药指纹图谱

【数据集背景】

本数据集源站标题为《Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma》。配套论文《Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0040521。源站首次发布：2012-08-08。

【数据内容】

源站原始描述：Background Pemetrexed, a multi-folate inhibitor combined with a platinum compound is the first-line treatment of malignant mesothelioma, but median survival is still one year. Intrinsic and acquired resistance to pemetrexed is common, but its biological basis is obscure. Here we report for the first time a genome-wide profile of acquired resistance in the tumour from an exceptional case with advanced pleural mesothelioma and almost six years survival after 39 cycles of second-line pemetrexed/car…

【数据结构与技术规格】

文件数 5 个，合计 979.33 KB。Figure_S1.tif：image/tiff，177.32 KB。Figure_S2.tif：image/tiff，126.65 KB。Figure_S3.tif：image/tiff，281.96 KB。数据集 DOI：10.1371/journal.pone.0040521。

【主题与分类】

源站学科分类：Cancer、Genetics。主题标签：molecular、fingerprint、pemetrexed、platinum、mesothelioma。

【适用方向】

源站学科分类标注为 Cancer、Genetics。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Molecular_Resistance_Fingerprint_of_Pemetrexed_and_Platinum_in_a_Long_Term_Survivor_of_Mesothelioma/121458

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Dimitri Røe, Oluf; Szulkin, Adam; Anderssen, Endre; Flatberg, Arnar; Sandeck, Helmut; Amundsen, Tore; et al. (2016). Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。