转移性髓母细胞瘤重塑局部软脑膜微环境以促进进一步转移定植和生长

资源简介

转移性髓母细胞瘤重塑局部软脑膜微环境以促进进一步转移定植和生长

【数据集背景】

本数据集源站标题为《Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth》。配套论文《Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth》发表于 Nature Cell Biology（2025），DOI：10.1038/s41556-025-01660-7。源站首次发布：2025-04-23。

【数据内容】

源站原始描述：Includes additional source images for Fig. 2f (GFP+ metastatic distribution along Ptch-SB spinal cord), Fig. 2g (GFP+ metastases and leptomeningeal blood vessels), Fig. 2h (Pdgfra-H2BeGFP fibroblast localization with leptomeningeal blood vessels), Extended Data Fig. 9a (BMP4 expression in SmoA1/SB spinal cord cross-sections), and Extended Data Fig. 9b (BMP7 expression in SmoA1/SB spinal cord cross-sections)

【数据结构与技术规格】

文件数 143 个，合计 828.64 MB。数据集 DOI：10.6084/m9.figshare.28637567.v1。

【主题与分类】

源站学科分类：Cancer。主题标签：medulloblastoma、genetically engineered mouse models、stereo microscopy、confocal micrographs。

【适用方向】

源站学科分类标注为 Cancer。

【获取与许可】

源站页面：https://springernature.figshare.com/articles/dataset/Metastatic_medulloblastoma_remodels_the_local_leptomeningeal_microenvironment_to_promote_further_metastatic_colonization_and_growth/28637567

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Abeysundara, Namal; Taylor, Michael D (2025). Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth. figshare. Dataset