越南非小细胞肺癌患者可操作突变谱

数据集获取（Figshare）

• 源站标题：Actionable mutational profiles of Vietnamese patients with NSCLC
• DOI：10.6084/m9.figshare.12501128.v2
• 发布日期：2020-06-17
• 文件数：1 个
• 文件总体积：144.18 KB
• 源站页面：https://figshare.com/articles/dataset/Actionable_mutational_profiles_of_Vietnamese_patients_with_NSCLC/12501128

命令行下载

curl -L -o "546441_Tran_Table_S2.xlsx" "https://ndownloader.figshare.com/files/23200004"

文件清单

• 546441_Tran_Table_S2.xlsx（144.18 KB）

文件总体积 144.18 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Population-specific profiling of mutations in cancer genes is of critical importance for the understanding of cancer biology in general as well as the establishment of optimal diagnostics and treatment guidelines for that particular population. Although genetic analysis of tumor tissue is often used to detect mutations in cancer genes, the invasiveness and limited accessibility hinders its application in large-scale population studies. In this study, we used ultra-deep massive parallel sequencing to compare actionable mutation profiles of two different cohorts of Vietnamese patients with non-small cell lung cancer (NSCLC). The first cohort, called cfDNA (cell free DNA) cohort, included plasma samples collected from a total of 265 treatment naive patients with advanced stage NSCLC (stage III-IV). The second cohort, called ttDNA (tumour tissue DNA) cohort, comprised of tissue samples from 285 NSCLC patients with matched tumour stages and treatment status of the cfDNA cohort. We found that ultra-deep sequencing of plasma cfDNA represents an alternative approach for population-wide genetic profiling of cancer genes where recruitment of patients is limited to the accessibility of tumour tissue site.

许可

CC0

引用

学术使用请引用 DOI 10.6084/m9.figshare.12501128.v2（source: https://figshare.com/articles/dataset/Actionable_mutational_profiles_of_Vietnamese_patients_with_NSCLC/12501128）。