来那度胺联合艾曲泊帕治疗症状性贫血的II期研究
该数据集来自 clinicaltrials.gov,属于肿瘤/白血病领域,聚焦来那度胺与艾曲泊帕联合治疗症状性贫血的II期研究

基本信息
资源简介
来那度胺联合艾曲泊帕治疗症状性贫血的II期研究
该数据集来自 clinicaltrials.gov,属于肿瘤/白血病领域,聚焦来那度胺与艾曲泊帕联合治疗症状性贫血的II期研究。覆盖成人骨髓增生异常综合征、贫血及慢性粒单核细胞白血病患者。数据可用于评估联合方案的血液学改善率、安全性、耐受性,以及改善时间、持续时间、血小板计数与输血、出血事件、骨髓与细胞遗传学反应、骨髓干细胞突变与疗效关系等,适合临床疗效与安全性预测分析(来源 clinicaltrials.gov)。
【数据内容】
源站描述(机器翻译,仅供参考):条件:成人骨髓增生异常综合征、贫血、慢性粒单核细胞白血病。主要目标(非结局指标):I. 评估艾曲泊帕(艾曲泊帕乙醇胺)/来那度胺联合方案的血液学改善率(依据修订版国际工作组[IWG]标准)。II. 评估联合方案的安全性和耐受性。次要目标(非结局指标):I. 比较血液学改善时间。II. 评估血液学改善持续时间。III. 评估联合治疗对血小板计数、血小板输注和出血事件的影响。IV. 评估骨髓反应频率(完全缓解[CR]+部分缓解[PR])和细胞遗传学反应。V. 评估骨髓干细胞突变与反应之间的关系。VI. 评估v
【主题与分类】
主题标签:Adult Myelodysplastic Syndrome、Anemia、Chronic Myelomonocytic Leukemia。本站分类:肿瘤/白血病。
【获取与许可】
源站页面:https://clinicaltrials.gov/study/NCT01772420
下载信息
注册下载
需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。
暂未开放公开下载
无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。
免登录有偿下载
公开数据集受托下载与技术交付服务。
提供高速下载与技术交付服务(收技术服务费,非数据销售)
暂未开放当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。
使用方式
数据集获取
源站:https://clinicaltrials.gov/study/NCT01772420
标准获取流程:
- 访问源站链接,注册/登录账号;
- 进入数据集详情页,按页面指引申请权限或直接下载;
- 部分平台提供 SDK,例如:
- OpenDataLab:
pip install openxlab后openxlab.dataset.get(...) - ModelScope:
pip install modelscope后modelscope download - 天池: 登录后页面提供直链下载
以源站「数据下载/使用文档」页面为准。
- OpenDataLab:
数据说明
Conditions: Adult Myelodysplastic Syndrome, Anemia, Chronic Myelomonocytic Leukemia. PRIMARY OBJECTIVES (not Outcome Measures): I. To evaluate the rate of hematologic improvement of the eltrombopag (eltrombopag olamine)/lenalidomide combination (as per Modified International Working Group [IWG] criteria). II. To evaluate the safety and tolerability of the combination. SECONDARY OBJECTIVES (not Outcome Measures): I. To compare the time to hematologic improvement. II. To evaluate the duration of hematologic improvement III. To evaluate the effect of combination treatment on platelet counts, platelet transfusions and bleeding events. IV. To evaluate the frequency of bone marrow response (complete response [CR] + partial response [PR]) and cytogenetic response. V. To evaluate the relationship between mutations in bone marrow stem cells and response. VI. To evaluate the relationship between various stem and progenitor alterations and response. OUTLINE: Patients are initially assigned to 1 of 2 treatment arms. ARM A: Patients with platelet counts ≥ 50,000 receive lenalidomide orally (PO) daily or every other day (QOD) on days 1-21. If platelet counts fall below 50,000, patients discontinue lenalidomide and receive eltrombopag olamine PO daily or QOD until platelet count is maintained above 50,000 for 2 weeks. Patients then resume lenalidomide PO daily or QOD. If platelets fall below 50,000 again, patients receive eltrombopag olamine as before. When platelet counts are maintained above 50,000 for 2 weeks, patients resume lenalidomide concurrently with eltrombopag for all subsequent courses. ARM B: Patients with platelet counts < 50,000 receive eltrombopag olamine PO daily or QOD on days 1-28 until platelet counts is maintained above 50,000 for 2 weeks. Patients then receive treatment as in Arm A. In both arms, treatment repeats every 28 days for 4 courses in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up every 3 months for 2 years, every 6 months for 3 years, and then every 12 mont
数据加载示例(图像类)
from PIL import Image
import glob, os
files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)
# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path) # 要求 子目录=类别
目录组织与标注格式以源站说明和下载后实际文件为准。
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