转移性组织学特殊类型浸润性乳腺癌基因组景观元数据记录

数据集获取（Figshare）

• 源站标题：Metadata record for the manuscript: The genomic landscape of metastatic histologic special types of invasive breast cancer
• DOI：10.6084/m9.figshare.12855149.v1
• 发布日期：2020-10-09
• 源站页面：https://springernature.figshare.com/articles/dataset/Metadata_record_for_the_manuscript_The_genomic_landscape_of_metastatic_histologic_special_types_of_invasive_breast_cancer/12855149

源站：https://figshare.com/articles/dataset/Metadata_record_for_the_manuscript_The_genomic_landscape_of_metastatic_histologic_special_types_of_invasive_breast_cancer/12855149

按页面 Download 按钮获取。

数据说明

Summary
This metadata record provides details of the data supporting the claims of the related manuscript: “The genomic landscape of metastatic histologic special types of invasive breast cancer ”. The related study aimed to define the repertoire of somatic genetic alterations of metastatic histologic special types of breast cancer. The study re-analyzed targeted capture sequencing data of 309 special types of breast cancer, including metastatic and primary invasive lobular carcinomas (n=132 and n=127, respectively), mixed mucinous (n=5 metastatic and n=14 primary), micropapillary (n=12 metastatic and n=8 primary) and metaplastic breast cancers (n=6 metastatic and n=5 primary), and compared metastatic histologic special types of breast cancer to metastatic invasive ductal carcinomas of no special type (IDC-NSTs) matched according to clinicopathologic characteristics and to primary special type breast cancers.

Data access
The data supporting the related study are as follows:

• Histologic images supporting Figures 1, 2, 3, 4, and Supplementary Figure 7: these are not publicly available, but can be requested from the corresponding author, Dr. Fresia Pareja.
• MSK-IMPACT sequencing data supporting Figures 1, 2, 3, 4, 5, Supplementary Figures 1, 2, 3, 4, 5, 6, and Supplementary Table 3, 4, 5: these data are publicly available in cBioPortal at the following accession: https://identifiers.org/cbioportal:breast_msk_2018
• Clinical data supporting supplementary Tables 1, 2, 5 and 6: these data are available in the original publication by Razavi et al (https://doi.org/10.1016/j.ccell.2018.08.008).

Corresponding author
Dr. Fresia Pareja
Memorial Sloan Kettering Cancer Center
Department of Pathology
1275 York Avenue
New York, NY 10065
United States
212-639-3707
parejaf@mskcc.org

Name of Institutional Review Board or ethics committee that approved the study
The study was approved by Memorial Sloan Kettering Cancer Center Institutional Review Board as part of the project whose findings were initially published by Razavi et al (2018). Informed consent was provided in the original study by Razavi et al “2018).

许可

CC0

引用

学术使用请引用 DOI 10.6084/m9.figshare.12855149.v1（source: https://springernature.figshare.com/articles/dataset/Metadata_record_for_the_manuscript_The_genomic_landscape_of_metastatic_histologic_special_types_of_invasive_breast_cancer/12855149）。