伊马替尼和达沙替尼对慢性髓系白血病细胞与纤维连接蛋白相互作用的实时分析数据集

资源简介

伊马替尼和达沙替尼对慢性髓系白血病细胞与纤维连接蛋白相互作用的实时分析数据集

【数据集背景】

本数据集源站标题为《Real-Time Analysis of Imatinib- and Dasatinib-Induced Effects on Chronic Myelogenous Leukemia Cell Interaction with Fibronectin》。配套论文《Real-Time Analysis of Imatinib- and Dasatinib-Induced Effects on Chronic Myelogenous Leukemia Cell Interaction with Fibronectin》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0107367。源站首次发布：2014-09-08。

【数据内容】

源站原始描述：Attachment of stem leukemic cells to the bone marrow extracellular matrix increases their resistance to chemotherapy and contributes to the disease persistence. In chronic myelogenous leukemia (CML), the activity of the fusion BCR-ABL kinase affects adhesion signaling. Using real-time monitoring of microimpedance, we studied in detail the kinetics of interaction of human CML cells (JURL-MK1, MOLM-7) and of control BCR-ABL-negative leukemia cells (HEL, JURKAT) with fibronectin-coated surface. The…

【数据结构与技术规格】

文件数 6 个，合计 1.23 MB。Figure_S1.pdf：application/pdf，27.75 KB。Figure_S2.pptx：application/vnd.openxmlformats-officedocument.presentationml.presentation，221.55 KB。Figure_S3.pptx：application/vnd.openxmlformats-officedocument.presentationml.presentation，96.81 KB。数据集 DOI：10.1371/journal.pone.0107367。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：CML cells、CML cell lines、interference reflection microscopy、lyn、bone marrow extracellular matrix increases、imatinib、CML cell interaction、EC 50、100 nM dasatinib、hel。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Real_Time_Analysis_of_Imatinib_and_Dasatinib_Induced_Effects_on_Chronic_Myelogenous_Leukemia_Cell_Interaction_with_Fibronectin_/1165372

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Obr, Adam; Röselová, Pavla; Grebeňová, Dana; Kuželová, Kateřina (2016). Real-Time Analysis of Imatinib- and Dasatinib-Induced Effects on Chronic Myelogenous Leukemia Cell Interaction with Fibronectin. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。