Name: 晚期肝内胆管癌联合免疫治疗病例报告表格2
Creator: 千方医数集科研发现管道
License: CC BY 4.0

基本信息

模态

表格

大小

0.000041079 GB

许可

CC BY 4.0

创建/更新时间

2026-10-07

版本

v1

资源简介

晚期肝内胆管癌联合免疫治疗病例报告表格2

【一句话概览】

本数据集是 figshare 公开的结构化表格数据集，收录 1 个文件、合计 41.08 KB，主题涵盖 intrahepatic cholangiocarcinoma、immunotherapy、conversion therapy、PD-L1、TMB，可用于统计建模、特征工程与队列分析，CC BY 4.0 许可开放获取。

【数据集背景】

本数据集源站标题为《Table_2_Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Combined With Tyrosine Kinase Inhibitors: A Case Report.xlsx》。配套论文《Lenvatinib plus checkpoint inhibitors in patients (pts) with advanced intrahepatic cholangiocarcinoma (ICC): Preliminary data and correlation with next-generation sequencing.》发表于 Journal of Clinical Oncology（2018），DOI：10.1200/JCO.2018.36.4_suppl.500。源站首次发布：2021-09-17。

【数据内容】

源站原始描述：Advanced intrahepatic cholangiocarcinoma (iCCA) is not suitable for surgical treatment. Guided by the concept of precision medicine, preoperative systematic treatment may reshape the clinical outcomes of advanced intrahepatic cholangiocarcinoma patients. We describe the case of a 38-year-old female who has been diagnosed with stage IV intrahepatic cholangiocarcinoma with a high tumor mutational burden and positively programmed death-ligand 1 (PD-L1) expression. The patient was treated with progr…

【数据结构与技术规格】

文件数 1 个，合计 41.08 KB。Table_2_Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Com.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，41.08 KB。数据集 DOI：10.3389/fimmu.2021.744571.s002。

【主题与分类】

源站学科分类：Transplantation Immunology、Tumour Immunology、Immunology not elsewhere classified、Immunology、Veterinary Immunology、Animal Immunology。主题标签：intrahepatic cholangiocarcinoma、immunotherapy、conversion therapy、PD-L1、TMB。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面：https://frontiersin.figshare.com/articles/dataset/Table_2_Successful_Treatment_of_Advanced_Intrahepatic_Cholangiocarcinoma_With_a_High_Tumor_Mutational_Burden_and_PD-L1_Expression_by_PD-1_Blockade_Combined_With_Tyrosine_Kinase_Inhibitors_A_Case_Report_xlsx/16634116

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Zhang, Ze; Zhang, Wenwen; Wang, Hongguang; Hu, Bingyang; Wang, Zhanbo; Lu, Shichun (2021). Table_2_Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Combined With Tyrosine Kinase Inhibitors: A Case Report.xlsx.…

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。

原始链接

https://figshare.com/articles/dataset/Table_2_Successful_Treatment_of_Advanced_Intrahepatic_Cholangiocarcinoma_With_a_High_Tumor_Mutational_Burden_and_PD-L1_Expression_by_PD-1_Blockade_Combined_With_Tyrosine_Kinase_Inhibitors_A_Case_Report_xlsx/16634116

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使用方式

数据集获取（Figshare）

源站标题：Table_2_Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Combined With Tyrosine Kinase Inhibitors: A Case Report.xlsx
DOI：10.3389/fimmu.2021.744571.s002
发布日期：2021-09-17
文件数：1 个
文件总体积：41.08 KB
源站页面：https://frontiersin.figshare.com/articles/dataset/Table_2_Successful_Treatment_of_Advanced_Intrahepatic_Cholangiocarcinoma_With_a_High_Tumor_Mutational_Burden_and_PD-L1_Expression_by_PD-1_Blockade_Combined_With_Tyrosine_Kinase_Inhibitors_A_Case_Report_xlsx/16634116

命令行下载

curl -L -o "Table_2_Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Com.xlsx" "https://ndownloader.figshare.com/files/30805957"

文件清单

Table_2_Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Com.xlsx（41.08 KB）

文件总体积 41.08 KB（源站 API 实测）。

数据说明

Advanced intrahepatic cholangiocarcinoma (iCCA) is not suitable for surgical treatment. Guided by the concept of precision medicine, preoperative systematic treatment may reshape the clinical outcomes of advanced intrahepatic cholangiocarcinoma patients. We describe the case of a 38-year-old female who has been diagnosed with stage IV intrahepatic cholangiocarcinoma with a high tumor mutational burden and positively programmed death-ligand 1 (PD-L1) expression. The patient was treated with programmed cell death 1 (PD-1) inhibitors combined with tyrosine kinase inhibitors (TKIs). After 7 cycles of combination therapy, she underwent radical resection and no tumor cells were found in the postoperative histopathological examination. In addition, the patient’s survival time had reached 25 months, as of August 2021. To date, this is the first case of successful radical resection after combined immunotherapy with TKIs for advanced PD-L1-positive intrahepatic cholangiocarcinoma with a high tumor mutational burden (TMB). The case provides a new approach to the treatment of advanced intrahepatic cholangiocarcinoma.