癌症DNA序列检测数据集

包含152种癌症的DNA序列数据集,用于癌症检测。

twi05twi05
GitHub
2022-12-07 更新
浏览 13
基因组癌症基因组

基本信息

模态
基因组
创建/更新时间
2022-12-07

资源简介

该数据集包含152种癌症类型及其对应的DNA序列,用于癌症检测任务。数据模态为基因组序列。

原始链接

https://github.com/twi05/detect-cancer-dna-sequence

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使用方式

数据集获取

git clone https://github.com/twi05/detect-cancer-dna-sequence.git

curl -L -o repo.zip https://github.com/twi05/detect-cancer-dna-sequence/archive/refs/heads/main.zip
unzip repo.zip

源站 README 摘录(使用方式)

detect-cancer-dna-sequence

Detect cancerous and non-cancerous DNA sequences from datasets, Using cpp programming language. One of application of LCS

Dataset Description:

Dataset consists of all types of cancer and its respective DNA Sequences. It consists of 152 types of cancer.

Approach Used:

The program accepts a 22-character-long string of a person’'s DNA sequence as input. It now looks for Longest Common Subsequences (LCS), which are similar to Cancer Genomes, which are also DNA Sequences. If the matched subsequence is found in more than 40% of cancer genomes, it concludes that cancer has been found and also indicates which cancer and stage it is in. Also data visualization is also done with help of Matplotlib of which primary cancers are in what stage.

Algorithm Used:

Using Dynamic Programming to find LCS
The following steps are followed for finding the longest common subsequence.

  1. Create a table of dimension n+1*m+1 where n and m are the lengths of X and Y respectively. The first row and the first column are filled with zeros.
    Fill each cell of the table using the following logic.
  2. If the character corresponding to the current row and current column are matching, then fill the current cell by adding one to the diagonal element. Point an arrow to the diagonal cell.
  3. Else take the maximum value from the previous column and previous row element for filling the current cell. Point an arrow to the cell with maximum value. If they are equal, point to any of them.
  4. Step 2 is repeated until the table is filled.
  5. The value in the last row and the last column is the length of the longest common subsequence.
  6. In order to find the longest common subsequence, start from the last element and follow the direction of the arrow. The elements corresponding to () symbol form the longest common subsequence.

Time Complexity:

In the dynamic algorithm, the results obtained from each comparison between elements of X and the elements of Y are stored in a table so that they can be used in future computations.
So, the time taken by a dynamic approach is the time taken to fill the table (ie. O(m*n)).

数据加载示例(表格/文本类)

import pandas as pd, glob, os

files = (glob.glob(os.path.join(path, "**", "*.csv"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tsv"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.xlsx"), recursive=True))
print("数据文件:", files)
df = pd.read_csv(files[0])
print(df.shape); print(df.columns.tolist()); print(df.head(3))

完整仓库:github.com/twi05/detect-cancer-dna-sequence

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