比较干扰素-γ释放试验与两种临界点结核菌素皮肤试验检测初级卫生保健工作者中潜伏结核感染的数据集

数据集获取（Figshare）

• 源站标题：Comparison of Interferon-γ Release Assay to Two Cut-Off Points of Tuberculin Skin Test to Detect Latent <i>Mycobacterium tuberculosis</i> Infection in Primary Health Care Workers
• DOI：10.1371/journal.pone.0102773
• 发布日期：2014-08-19
• 文件数：2 个
• 文件总体积：183.29 KB
• 源站页面：https://plos.figshare.com/articles/dataset/Comparison_of_Interferon_Release_Assay_to_Two_Cut_Off_Points_of_Tuberculin_Skin_Test_to_Detect_Latent_i_Mycobacterium_tuberculosis_i_Infection_in_Primary_Health_Care_Workers/2683945

命令行下载

curl -L -o "Questionnaire S1.pdf" "https://ndownloader.figshare.com/files/4352014"
curl -L -o "Questionnaire S2.pdf" "https://ndownloader.figshare.com/files/4352017"

文件清单

• Questionnaire S1.pdf（102.02 KB）
• Questionnaire S2.pdf（81.27 KB）

文件总体积 183.29 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
An interferon-γ release assay, QuantiFERON-TB (QFT) test, has been introduced an alternative test for the diagnosis of latent Mycobacterium tuberculosis infection (LTBI). Here, we compared the performance of QFT with tuberculin skin test (TST) measured at two different cut-off points among primary health care work (HCW) in Brazil.
Methods
A cross-sectional study was carried out among HCWs in four Brazilian cities with a known history of high incidence of TB. Results of the QFT were compared to TST results based on both ≥5 mm and ≥10 mm as cut-off points.
Results
We enrolled 632 HCWs. When the cut-off value of ≥10 mm was used, agreement between QFT and TST was 69% (k = 0.31), and when the cut-off of ≥5 mm was chosen, the agreement was 57% (k = 0.22). We investigated possible factors of discordance of TST vs QFT. Compared to the TST−/QFT− group, risk factors for discordance in the TST+/QFT− group with TST cut-off of ≥5 mm included age between 41–45 years [OR = 2.70; CI 95%: 1.32–5.51] and 46–64 years [OR = 2.04; CI 95%: 1.05–3.93], BCG scar [OR = 2.72; CI 95%: 1.40–5.25], and having worked only in primary health care [OR = 2.30; CI 95%: 1.09–4.86]. On the other hand, for the cut-off of ≥10 mm, BCG scar [OR = 2.26; CI 95%: 1.03–4.91], being a household contact of a TB patient [OR = 1.72; CI 95%: 1.01–2.92] and having had a previous TST [OR = 1.66; CI 95%: 1.05–2.62], were significantly associated with the TST+/QFT− group. No statistically significant associations were found among the TST−/QFT+ discordant group with either TST cut-off value.
Conclusions
Although we identified BCG vaccination to contribute to the discordance at both TST cut-off measures, the current Brazilian recommendation for the initiation of LTBI treatment, based on information gathered from medical history, TST, chest radiograph and physical examination, should not be changed.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0102773（source: https://plos.figshare.com/articles/dataset/Comparison_of_Interferon_Release_Assay_to_Two_Cut_Off_Points_of_Tuberculin_Skin_Test_to_Detect_Latent_i_Mycobacterium_tuberculosis_i_Infection_in_Primary_Health_Care_Workers/2683945）。