革兰染色和生化检测结果

基于加纳156例患者标本的细菌培养、革兰染色、生化鉴定和药敏试验表格数据,用于抗菌药物耐药监测。

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表格tertiary healthcare facilitiesstaphylococcus aureus </shalina health centreprimary healthcare settingsprimary healthcare facilityoptimize treatment protocolslaboratory standards instituteklebsiella pneumoniae </infection control measuresescherichia coli </empirical antibiotic usebased prescribing practices
Gram stain and biochemical test results.

基本信息

模态
表格
大小
0.000021481 GB
许可
CC BY 4.0
创建/更新时间
2026-10-10
版本
v1

资源简介

革兰染色和生化检测结果

【一句话概览】

本数据集是 figshare 公开的结构化表格数据集,收录 1 个文件、合计 21.48 KB,主题涵盖 tertiary healthcare facilities、shalina health centre、primary healthcare settings、primary healthcare facility、optimize treatment protocols,可用于统计建模、特征工程与队列分析,CC BY 4.0 许可开放获取。

【数据集背景】

本数据集源站标题为《Gram stain and biochemical test results.》。源站首次发布:2025-08-06。

【数据内容】

源站原始描述:Antimicrobial resistance (AMR) is a global public health crisis, particularly in low- and middle-income countries where empirical antibiotic use is common. Data on bacterial resistance patterns in primary healthcare settings remain limited in Ghana, impeding effective treatment guidelines and infection control measures. This cross-sectional study, conducted at Shalina Health Centre in Accra, Ghana, between May and November 2024, examined bacterial infections among 156 systematically sampled pati…

中文译文(机器翻译,仅供快速理解,请以原文为准):抗微生物药物耐药性(AMR)是一场全球公共卫生危机,在经验性使用抗生素较为普遍的低收入和中等收入国家尤为突出。在加纳,基层医疗机构的细菌耐药模式数据仍然有限,阻碍了有效治疗指南和感染控制措施的制定。这项横断面研究于2024年5月至11月在加纳阿克拉的Shalina Health Centre开展,对156名系统抽样患者的细菌感染情况进行了检查。临床标本经过细菌培养、革兰染色和生化试验鉴定,并采用Kirby-Bauer纸片扩散法进行抗生素敏感性试验。根据临床和实验室标准协会(CLSI)指南评估超广谱β-内酰胺酶(ESBL)产生情况。统计分析包括采用95%置信区间进行患病率估计,以及使用方差分析和卡方检验进行亚组比较。在62.20%[97/156]的参与者中检测到细菌感染,其中大肠埃希菌[43.30%]、金黄色葡萄球菌[21.65%]和肺炎克雷伯菌[19.59%]是最常见的病原体。革兰阴性菌占分离株的75.26%。女性的感染率[69.64%]显著高于男性43.18%。多重耐药(MDR)普遍存在[97.94%],且76.06%的肠杆菌科分离株为ESBL产生菌。革兰阴性分离株对氟喹诺酮类、头孢菌素类和β-内酰胺类的耐药性尤其高。该研究凸显了基层医疗机构中多重耐药细菌的高负担,以及对关键抗生素的显著耐药性。这些发现强调,迫切需要加强抗微生物药物管理、循证处方实践和感染预防措施。在非三级医疗机构开展监测对于减轻加纳及类似环境中的AMR传播和优化治疗方案至关重要。

【数据结构与技术规格】

文件数 1 个,合计 21.48 KB。pgph.0004991.s001.xlsx:application/vnd.openxmlformats-officedocument.spreadsheetml.sheet,21.48 KB。数据集 DOI:10.1371/journal.pgph.0004991.s001。

【主题与分类】

源站学科分类:Medicine、Microbiology、Cell Biology、Biotechnology、Immunology、Cancer。主题标签:tertiary healthcare facilities、shalina health centre、primary healthcare settings、primary healthcare facility、optimize treatment protocols、laboratory standards institute、infection control measures、empirical antibiotic use、based prescribing practices、assessed per clinical。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面:https://plos.figshare.com/articles/dataset/Gram_stain_and_biochemical_test_results_/29845981

使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。

规范引用:Aboagye, Frank Twum; Ahiabu, Mawutor Kwame; Akahoho, Hannah Segbefiah; Armah, Emmanuel; Anang, Samuel G.; Amarteifio, Naa A. S.; et al. (2025). Gram stain and biochemical test results.. PLOS Global Public Health. Dataset

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使用方式

数据集获取(Figshare)

命令行下载

curl -L -o "pgph.0004991.s001.xlsx" "https://ndownloader.figshare.com/files/56973364"

文件清单

  • pgph.0004991.s001.xlsx(21.48 KB)

文件总体积 21.48 KB(源站 API 实测)。

数据说明

Antimicrobial resistance (AMR) is a global public health crisis, particularly in low- and middle-income countries where empirical antibiotic use is common. Data on bacterial resistance patterns in primary healthcare settings remain limited in Ghana, impeding effective treatment guidelines and infection control measures. This cross-sectional study, conducted at Shalina Health Centre in Accra, Ghana, between May and November 2024, examined bacterial infections among 156 systematically sampled patients. Clinical specimens underwent bacterial culture, identification via Gram staining and biochemical tests, and antibiotic susceptibility testing using the Kirby-Bauer disc diffusion method. Extended-spectrum beta-lactamase (ESBL) production was assessed per Clinical and Laboratory Standards Institute (CLSI) guidelines. Statistical analysis included prevalence estimation with 95% confidence intervals and subgroup comparisons using ANOVA and Chi-square tests. Bacterial infections were detected in 62.20% [97/156] of participants, with Escherichia coli [43.30%], Staphylococcus aureus [21.65%], and Klebsiella pneumoniae [19.59%] as the most prevalent pathogens. Gram-negative bacteria accounted for 75.26% of isolates. Females exhibited a significantly higher infection rate [69.64%] than males [43.18%] [p = 0.002]. Multidrug resistance (MDR) was widespread [97.94%], and 76.06% of Enterobacteriaceae isolates were ESBL producers. Resistance to fluoroquinolones, cephalosporins, and beta-lactams was particularly high among Gram-negative isolates. The study highlights the high burden of multidrug-resistant bacteria in primary healthcare settings, with significant resistance to key antibiotics. These findings emphasize the urgent need for enhanced antimicrobial stewardship, evidence-based prescribing practices, and strengthened infection prevention measures. Surveillance in non-tertiary healthcare facilities is crucial to mitigate AMR transmission and optimize treatment protocols in Ghana and similar settings.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pgph.0004991.s001(source: https://plos.figshare.com/articles/dataset/Gram_stain_and_biochemical_test_results_/29845981)。

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