DataSheet1：用于湿组织伤口敷料的负载CeO2量子点抗菌抗炎聚乙烯亚胺/聚丙烯酸水凝胶

数据集获取（Figshare）

• 源站标题：DataSheet1_Antibacterial and anti-inflammatory polyethyleneimine/polyacrylic acid hydrogel loaded with CeO2 quantum dots for wet tissue wound dressings.docx
• DOI：10.3389/fmats.2024.1379836.s001
• 发布日期：2024-04-11
• 文件数：1 个
• 文件总体积：2.21 MB
• 源站页面：https://frontiersin.figshare.com/articles/dataset/DataSheet1_Antibacterial_and_anti-inflammatory_polyethyleneimine_polyacrylic_acid_hydrogel_loaded_with_CeO2_quantum_dots_for_wet_tissue_wound_dressings_docx/25584321

命令行下载

curl -L -o "DataSheet1_Antibacterial and anti-inflammatory polyethyleneimine/polyacrylic acid hydrogel loaded with CeO2 quantum dots for wet tissue wound dressing.docx" "https://ndownloader.figshare.com/files/45583764"

文件清单

• DataSheet1_Antibacterial and anti-inflammatory polyethyleneimine/polyacrylic acid hydrogel loaded with CeO2 quantum dots for wet tissue wound dressing.docx（2.21 MB）

文件总体积 2.21 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Searching for an antibacterial and anti-inflammatory dressing that can stably adhere to wet tissues remains a momentous clinical challenge, especially in the context of treatment failure due to multi-drug-resistant bacteria. Using a hard template method in combination with an in situ chelating strategy, three-dimensional nitrogen-doped graded porous carbon anchored 1.5–2.5 nm CeO2 quantum dots (CeO2-QDs) were tailor-designed in this study. Using the size effect, CeO2-QDs have a higher percentage of Ce3+ and oxygen vacancies that could amplify their antibacterial effects. Polyethyleneimine/polyacrylic acid (PEA) powder could self-gel and be adhesive due to its strong physical interactions, which make it an ideal carrier for CeO2-QDs. PEA@50 (mg/mL) CeO2-QDs hydrogel and PEA@75 (mg/mL) CeO2-QDs hydrogel with moderate doses of CeO2-QDs show a superior antibacterial effect against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) strains. Furthermore, PEA@50CeO2-QDs hydrogels possess excellent anti-inflammatory capacity through their antioxidant activity, which could promote macrophage M2 phenotype polarization. More importantly, cytotoxicity assays on L929 fibroblasts show that PEA@CeO2-QDs hydrogels have no significant toxicity, and a significant proliferative effect could be observed. Overall, PEA@50CeO2-QDs hydrogels have the potential to become a multifunctional wet tissue dressing with anti-inflammatory and antiseptic properties to promote the healing of infected wounds.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.3389/fmats.2024.1379836.s001（source: https://frontiersin.figshare.com/articles/dataset/DataSheet1_Antibacterial_and_anti-inflammatory_polyethyleneimine_polyacrylic_acid_hydrogel_loaded_with_CeO2_quantum_dots_for_wet_tissue_wound_dressings_docx/25584321）。