南非产前诊所即时CD4检测成本效果分析数据集

数据集获取（Figshare）

• 源站标题：Point-of-Care CD4 Testing to Inform Selection of Antiretroviral Medications in South African Antenatal Clinics: A Cost-Effectiveness Analysis
• DOI：10.1371/journal.pone.0117751
• 发布日期：2015-03-10
• 文件数：7 个
• 文件总体积：873.30 KB
• 源站页面：https://plos.figshare.com/articles/dataset/_Point_of_Care_CD4_Testing_to_Inform_Selection_of_Antiretroviral_Medications_in_South_African_Antenatal_Clinics_A_Cost_Effectiveness_Analysis_/1330805

命令行下载

curl -L -o "S1_Appendix.docx" "https://ndownloader.figshare.com/files/1942645"
curl -L -o "S1_Fig.tif" "https://ndownloader.figshare.com/files/1942646"
curl -L -o "S2_Fig.tif" "https://ndownloader.figshare.com/files/1942647"
curl -L -o "S1_Table.docx" "https://ndownloader.figshare.com/files/1942648"
curl -L -o "S2_Table.docx" "https://ndownloader.figshare.com/files/1942649"
curl -L -o "S3_Table.docx" "https://ndownloader.figshare.com/files/1942650"
curl -L -o "S4_Table.docx" "https://ndownloader.figshare.com/files/1942651"

文件清单

• S1_Appendix.docx（45.02 KB）
• S1_Fig.tif（271.57 KB）
• S2_Fig.tif（468.67 KB）
• S1_Table.docx（32.93 KB）
• S2_Table.docx（14.35 KB）
• S3_Table.docx（26.48 KB）
• S4_Table.docx（14.28 KB）

文件总体积 873.30 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
Many prevention of mother-to-child HIV transmission (PMTCT) programs currently prioritize antiretroviral therapy (ART) for women with advanced HIV. Point-of-care (POC) CD4 assays may expedite the selection of three-drug ART instead of zidovudine, but are costlier than traditional laboratory assays.
Methods
We used validated models of HIV infection to simulate pregnant, HIV-infected women (mean age 26 years, gestational age 26 weeks) in a general antenatal clinic in South Africa, and their infants. We examined two strategies for CD4 testing after HIV diagnosis: laboratory (test rate: 96%, result-return rate: 87%, cost: $14) and POC (test rate: 99%, result-return rate: 95%, cost: $26). We modeled South African PMTCT guidelines during the study period (WHO “Option A”): antenatal zidovudine (CD4 ≤350/μL) or ART (CD4>350/μL). Outcomes included MTCT risk at weaning (age 6 months), maternal and pediatric life expectancy (LE), maternal and pediatric lifetime healthcare costs (2013 USD), and cost-effectiveness ($/life-year saved).
Results
In the base case, laboratory led to projected MTCT risks of 5.7%, undiscounted pediatric LE of 53.2 years, and undiscounted PMTCT plus pediatric lifetime costs of $1,070/infant. POC led to lower modeled MTCT risk (5.3%), greater pediatric LE (53.4 years) and lower PMTCT plus pediatric lifetime costs ($1,040/infant). Maternal outcomes following laboratory were similar to POC (LE: 21.2 years; lifetime costs: $23,860/person). Compared to laboratory, POC improved clinical outcomes and reduced healthcare costs.
Conclusions
In antenatal clinics implementing Option A, the higher initial cost of a one-time POC CD4 assay will be offset by cost-savings from prevention of pediatric HIV infection.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0117751（source: https://plos.figshare.com/articles/dataset/_Point_of_Care_CD4_Testing_to_Inform_Selection_of_Antiretroviral_Medications_in_South_African_Antenatal_Clinics_A_Cost_Effectiveness_Analysis_/1330805）。