新生儿中心静脉导管相关血流感染的微生物组特征

数据集获取（Figshare）

• 源站标题：Microbiome signatures in neonatal central line associated bloodstream infections
• DOI：10.1371/journal.pone.0227967
• 发布日期：2020-01-16
• 文件数：9 个
• 文件总体积：3.90 MB
• 源站页面：https://plos.figshare.com/articles/dataset/Microbiome_signatures_in_neonatal_central_line_associated_bloodstream_infections/11630211

命令行下载

curl -L -o "pone.0227967.s001.pdf" "https://ndownloader.figshare.com/files/21089565"
curl -L -o "pone.0227967.s002.pdf" "https://ndownloader.figshare.com/files/21089568"
curl -L -o "pone.0227967.s003.tif" "https://ndownloader.figshare.com/files/21089571"
curl -L -o "pone.0227967.s004.tif" "https://ndownloader.figshare.com/files/21089577"
curl -L -o "pone.0227967.s005.tif" "https://ndownloader.figshare.com/files/21089580"
curl -L -o "pone.0227967.s006.docx" "https://ndownloader.figshare.com/files/21089583"
curl -L -o "pone.0227967.s007.docx" "https://ndownloader.figshare.com/files/21089586"
curl -L -o "pone.0227967.s008.docx" "https://ndownloader.figshare.com/files/21089589"

文件清单

• pone.0227967.s001.pdf（237.12 KB）
• pone.0227967.s002.pdf（37.93 KB）
• pone.0227967.s003.tif（430.21 KB）
• pone.0227967.s004.tif（2.45 MB）
• pone.0227967.s005.tif（674.12 KB）
• pone.0227967.s006.docx（20.14 KB）
• pone.0227967.s007.docx（15.53 KB）
• pone.0227967.s008.docx（16.06 KB）
• pone.0227967.s009.docx（15.86 KB）

文件总体积 3.90 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Neonates are at high risk for central line associated bloodstream infections (CLABSI). Biofilm formation is universal on indwelling catheters but why some biofilms seed the bloodstream to cause CLABSI is not clearly understood. With the objective to test the hypothesis that catheter biofilm microbiome in neonates with CLABSI differs than those without infection, we prospectively enrolled neonates (n = 30) with infected and uninfected indwelling central catheters. Catheters were collected at the time of removal, along with blood samples and skin swabs at the catheter insertion sites. Microbiomes of catheter biofilms, skin swabs and blood were evaluated by profiling the V4 region of the bacterial 16S rRNA gene using Illumina MiSeq sequencing platform. The microbial DNA load was higher from catheter biofilms of CLABSI patients without differences in alpha diversity when compared to that of the non-CLABSI neonates. Proteus and unclassified Staphylococcaceae were more abundant in infected catheter biofilms while Bradyrhizobium, Cloacibacterium, and Sphingomonas were more abundant in the uninfected catheters. A blood microbiome was detected in uninfected samples. The blood microbiome in CLABSI neonates clustered separately from the uninfected blood samples in beta diversity plots. We found that the microbiome signature in catheter biofilm and blood of neonates with CLABSI is different than the microbiomes of non-CLABSI neonates.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0227967（source: https://plos.figshare.com/articles/dataset/Microbiome_signatures_in_neonatal_central_line_associated_bloodstream_infections/11630211）。