氯己定醇与聚维酮碘醇预防血管内导管相关血流感染的成本效果分析

数据集获取（Figshare）

• 源站标题：Cost-effectiveness analysis of chlorhexidine-alcohol versus povidone iodine-alcohol solution in the prevention of intravascular-catheter-related bloodstream infections in France
• DOI：10.1371/journal.pone.0197747
• 发布日期：2018-05-25
• 文件数：9 个
• 文件总体积：551.07 KB
• 源站页面：https://plos.figshare.com/articles/dataset/Cost-effectiveness_analysis_of_chlorhexidine-alcohol_versus_povidone_iodine-alcohol_solution_in_the_prevention_of_intravascular-catheter-related_bloodstream_infections_in_France/6357782

命令行下载

curl -L -o "pone.0197747.s001.docx" "https://ndownloader.figshare.com/files/11662730"
curl -L -o "pone.0197747.s002.docx" "https://ndownloader.figshare.com/files/11662739"
curl -L -o "pone.0197747.s003.docx" "https://ndownloader.figshare.com/files/11662745"
curl -L -o "pone.0197747.s004.docx" "https://ndownloader.figshare.com/files/11662748"
curl -L -o "pone.0197747.s005.docx" "https://ndownloader.figshare.com/files/11662754"
curl -L -o "pone.0197747.s006.docx" "https://ndownloader.figshare.com/files/11662757"
curl -L -o "pone.0197747.s007.docx" "https://ndownloader.figshare.com/files/11662763"
curl -L -o "pone.0197747.s008.docx" "https://ndownloader.figshare.com/files/11662766"

文件清单

• pone.0197747.s001.docx（12.73 KB）
• pone.0197747.s002.docx（12.25 KB）
• pone.0197747.s003.docx（12.44 KB）
• pone.0197747.s004.docx（11.70 KB）
• pone.0197747.s005.docx（19.13 KB）
• pone.0197747.s006.docx（16.23 KB）
• pone.0197747.s007.docx（14.29 KB）
• pone.0197747.s008.docx（422.54 KB）
• pone.0197747.s009.docx（29.75 KB）

文件总体积 551.07 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Objective
To perform a cost-effectiveness analysis of skin antiseptic solutions (chlorhexidine-alcohol (CHG) versus povidone iodine-alcohol solution (PVI)) for the prevention of intravascular-catheter-related bloodstream infections (CRBSI) in intensive care unit (ICU) in France based on an open-label, multicentre, randomised, controlled trial (CLEAN).
Design
A 100-day time semi-markovian model was performed to be fitted to longitudinal individual patient data from CLEAN database. This model includes eight health states and probabilistic sensitivity analyses on cost and effectiveness were performed. Costs of intensive care unit stay are based on a French multicentre study and the cost-effectiveness criterion is the cost per patient with catheter-related bloodstream infection avoided.
Patients
2,349 patients (age≥18 years) were analyzed to compare the 1-time CHG group (CHG-T1, 588 patients), the 4-time CHG group (CHG-T4, 580 patients), the 1-time PVI group (PVI-T1, 587 patients), and the 4-time PVI group (PVI-T4, 594 patients).
Intervention
2% chlorhexidine-70% isopropyl alcohol (chlorhexidine-alcohol) compared to 5% povidone iodine-69% ethanol (povidone iodine-alcohol).
Results
The mean cost per alive, discharged or dead patient was of €23,798 (95% confidence interval: €20,584; €34,331), €21,822 (€18,635; €29,701), €24,874 (€21,011; €31,678), and €24,201 (€20,507; €29,136) for CHG-T1, CHG-T4, PVI-T1, and PVI-T4, respectively. The mean number of patients with CRBSI per 1000 patients was of 3.49 (0.42; 12.57), 6.82 (1.86; 17.38), 26.04 (14.64; 42.58), and 23.05 (12.32; 39.09) for CHG-T1, CHG-T4, PVI-T1, and PVI-T4, respectively. In comparison to the 1-time PVI solution, the 1-time CHG solution avoids 22.55 CRBSI /1,000 patients, and saves €1,076 per patient. This saving is not statistically significant at a 0.05 level because of the overlap of 95% confidence intervals for mean costs per patient in each group. Conversely, the difference in effectiveness between the CHG-T1 solution and the PVI-T1 solution is statistically significant.
Conclusions
The CHG-T1 solution is more effective at the same cost than the PVI-T1 solution. CHG-T1, CHG-T4 and PVI-T4 solutions are s

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0197747（source: https://plos.figshare.com/articles/dataset/Cost-effectiveness_analysis_of_chlorhexidine-alcohol_versus_povidone_iodine-alcohol_solution_in_the_prevention_of_intravascular-catheter-related_bloodstream_infections_in_France/6357782）。