T细胞大颗粒淋巴细胞白血病生存网络的动力学与结构分析数据集

资源简介

T细胞大颗粒淋巴细胞白血病生存网络的动力学与结构分析数据集

【数据集背景】

本数据集源站标题为《Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia》。配套论文《Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia》发表于 PLoS Computational Biology（2011），DOI：10.1371/journal.pcbi.1002267。源站首次发布：2011-11-10。

【数据内容】

源站原始描述：The blood cancer T cell large granular lymphocyte (T-LGL) leukemia is a chronic disease characterized by a clonal proliferation of cytotoxic T cells. As no curative therapy is yet known for this disease, identification of potential therapeutic targets is of immense importance. In this paper, we perform a comprehensive dynamical and structural analysis of a network model of this disease. By employing a network reduction technique, we identify the stationary states (fixed points) of the system, re…

【数据结构与技术规格】

文件数 4 个，合计 380.91 KB。Figure_S1.tif：image/tiff，302.79 KB。Table_S1.pdf：application/pdf，29.42 KB。Table_S2.pdf：application/pdf，35.08 KB。数据集 DOI：10.1371/journal.pcbi.1002267。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：dynamical、identifies、therapeutic、targets、granular、lymphocyte、leukemia。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Dynamical_and_Structural_Analysis_of_a_T_Cell_Survival_Network_Identifies_Novel_Candidate_Therapeutic_Targets_for_Large_Granular_Lymphocyte_Leukemia/131625

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Saadatpour, Assieh; Wang, Rui-Sheng; Liao, Aijun; Liu, Xin; P. Loughran, Thomas; Albert, István; et al. (2016). Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia. PLOS Computational Biology. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。