美国血友病B管理的终身成本：来自决策分析模型的付款人和社会视角数据集

数据集获取（Figshare）

• 源站标题：Adult lifetime cost of hemophilia B management in the US: payer and societal perspectives from a decision analytic model
• DOI：10.6084/m9.figshare.14043509.v2
• 发布日期：2021-03-02
• 文件数：4 个
• 文件总体积：261.99 KB
• 源站页面：https://tandf.figshare.com/articles/dataset/Adult_lifetime_cost_of_hemophilia_B_management_in_the_US_Payer_and_societal_perspectives_from_a_decision_analytic_model/14043509

命令行下载

curl -L -o "ijme_a_1891088_sm8883.docx" "https://ndownloader.figshare.com/files/26666771"
curl -L -o "ijme_a_1891088_sm9423.docx" "https://ndownloader.figshare.com/files/26666774"
curl -L -o "ijme_a_1891088_sm9219.jpg" "https://ndownloader.figshare.com/files/26491910"
curl -L -o "ijme_a_1891088_sm9146.jpg" "https://ndownloader.figshare.com/files/26491913"

文件清单

• ijme_a_1891088_sm8883.docx（11.91 KB）
• ijme_a_1891088_sm9423.docx（25.10 KB）
• ijme_a_1891088_sm9219.jpg（119.37 KB）
• ijme_a_1891088_sm9146.jpg（105.62 KB）

文件总体积 261.99 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Hemophilia B (HB) is a rare congenital disorder characterized by bleeding-related complications which are managed by prophylactic or post-bleeding event (“on-demand”) replacement of clotting factor IX (FIX). The standard of care for severe HB is life-long prophylaxis with standard half-life (SHL) or extended half-life (EHL) products given every 2–3 or 7–14 days, respectively. FIX treatment costs in the US have been investigated, but the lifetime costs of HB treatment have not been well characterized, particularly related to the impact of joint health deterioration and associated health resource utilization. We developed a decision-analytic model to explore outcomes, costs and underlying cost drivers associated with FIX treatment options over the lifetime of an adult with severe or moderately severe HB.
With participation from clinicians, health technology assessment specialists and patient advocates, a Markov model was constructed to estimate bleeding events and costs associated with health states including “bleed into joint”, “bleed not into joint”, “no bleed” and “death”. Sub-models of joint health were based on 0, 1, or ≥2 areas of chronic joint damage. US third-party payer and societal perspectives were considered with a lifetime horizon; sensitivity analyses tested the robustness of primary findings.
Total adult lifetime costs per patient with severe and moderately severe HB were $21,086,607 for SHL FIX prophylaxis, $22,987,483 for EHL FIX prophylaxis, and $20,971,826 for on-demand FIX treatment. For FIX prophylaxis, the cost of FIX treatment accounts for >90% of the total HB treatment costs.
This decision analytic model demonstrated significant economic burden associated with the current HB treatment paradigm.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.14043509.v2（source: https://tandf.figshare.com/articles/dataset/Adult_lifetime_cost_of_hemophilia_B_management_in_the_US_Payer_and_societal_perspectives_from_a_decision_analytic_model/14043509）。