RANKL（TNFSF11）依赖性骨石化症在Msx2缺失突变小鼠牙齿表型中的作用

资源简介

RANKL（TNFSF11）依赖性骨石化症在Msx2缺失突变小鼠牙齿表型中的作用

【数据集背景】

本数据集源站标题为《Role of RANKL (TNFSF11)-Dependent Osteopetrosis in the Dental Phenotype of Msx2 Null Mutant Mice》。配套论文《Role of RANKL (TNFSF11)-Dependent Osteopetrosis in the Dental Phenotype of Msx2 Null Mutant Mice》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0080054。源站首次发布：2013-11-21。

【数据内容】

源站原始描述：The MSX2 homeoprotein is implicated in all aspects of craniofacial skeletal development. During postnatal growth, MSX2 is expressed in all cells involved in mineralized tissue formation and plays a role in their differentiation and function. Msx2 null (Msx2−/−) mice display complex craniofacial skeleton abnormalities with bone and tooth defects. A moderate form osteopetrotic phenotype is observed, along with decreased expression of RANKL (TNFSF11), the main osteoclast-differentiating factor. In…

【数据结构与技术规格】

文件数 4 个，合计 3.10 MB。Figure_S1.tif：image/tiff，623.17 KB。Figure_S2.tif：image/tiff，2.04 MB。Figure_S3.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，105.57 KB。数据集 DOI：10.1371/journal.pone.0080054。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：rankl、osteopetrosis、dental、phenotype、null、mutant、mice。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Role_of_RANKL_TNFSF11_Dependent_Osteopetrosis_in_the_Dental_Phenotype_of_Msx2_Null_Mutant_Mice/859250

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Castaneda, Beatriz; Simon, Yohann; Ferbus, Didier; Robert, Benoit; Chesneau, Julie; Mueller, Christopher; et al. (2016). Role of RANKL (TNFSF11)-Dependent Osteopetrosis in the Dental Phenotype of Msx2 Null Mutant Mice. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。