1,4,5-三磷酸肌醇受体2型与慢性肾脏病-矿物质骨异常中的骨-血管轴相关

资源简介

1,4,5-三磷酸肌醇受体2型与慢性肾脏病-矿物质骨异常中的骨-血管轴相关

【数据集背景】

本数据集源站标题为《Inositol 1,4,5-trisphosphate receptor type 2 is associated with the bone–vessel axis in chronic kidney disease–mineral bone disorder》。配套论文《Inositol 1,4,5-trisphosphate receptor type 2 is associated with the bone–vessel axis in chronic kidney disease–mineral bone disorder》发表于 Renal Failure（2023），DOI：10.1080/0886022X.2022.2162419。项目资助方：This work was supported by the National Natural Science Foundation of China [U21A20349, 82270729, 81700607, 8170742, 82070690, 81970641 and 81800613]; the PHD Foundation of Sichuan Academy of Sciences & Sichuan Provincial People’s Hospital [2015BS05]; the Fundamental Research Funds for the Central Universities from UESTC [ZYGX2019J105]; Key R & D projects in Sichuan Province [2019YFS0538 and 2021YFS0370]; the Department of Science and Technology of Sichuan Province [2020ZYD034 and 2021YFS0372]; the Foundation of Health and Family Planning Commission in Sichuan [16PJ424]; the Foundation of Sichuan Medical Association [S20071]; the Zhongguancun Nephrology & Blood Purification Innovation Alliance [NBPIA20QC0102] and the Discipline Construction Fund of Sichuan Provincial People’s Hospital.。源站首次发布：2023-01-16。

【数据内容】

源站原始描述：The pathogenesis of renal osteopathy and cardiovascular disease suggests the disordered bone–vessel axis in chronic kidney disease–mineral bone disorder (CKD–MBD). However, the mechanism of the bone–vessel axis in CKD–MBD remains unclear. We established a CKD–MBD rat model to observe the pathophysiological phenotype of the bone–vessel axis and performed RNA sequencing of aortas to identify novel targets of the bone–vessel axis in CKD–MBD. The microarchitecture of the femoral trabecular bone dete…

【数据结构与技术规格】

文件数 8 个，合计 30.36 MB。irnf_a_2162419_sm7554.pdf：application/pdf，90.27 KB。irnf_a_2162419_sm7539.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，13.30 KB。irnf_a_2162419_sm7533.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，10.20 KB。数据集 DOI：10.6084/m9.figshare.21904346.v1。

【主题与分类】

源站学科分类：Biochemistry、Medicine、Cell Biology、Genetics、Physiology、Ecology。主题标签：Bone–vessel axis、chronic kidney disease–mineral bone disorder、clinical relevance、inositol 1,4,5-trisphosphate receptor type 2、vascular calcification。

【适用方向】

源站学科分类标注为 Biochemistry、Medicine、Cell Biology、Genetics、Physiology、Ecology。

【获取与许可】

源站页面：https://tandf.figshare.com/articles/dataset/Inositol_1_4_5-trisphosphate_receptor_type_2_is_associated_with_the_bone_vessel_axis_in_chronic_kidney_disease_mineral_bone_disorder/21904346

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Inositol 1,4,5-trisphosphate receptor type 2 is associated with the bone–vessel axis in chronic kidney disease–mineral bone disorder. Taylor & Francis. Xiao, Qiong; Tang, Yun; Luo, Haojun; Chen, Sipei; Tang, Qiao; Chen, Rong; et al

【使用注意】

· 源站最后修改于 2025-05-09，引用时请注意版本时效。