男性不育症的遗传与表观遗传学特征分析

资源简介

男性不育症的遗传与表观遗传学特征分析

【数据集背景】

本数据集源站标题为《Genetic and epigenetic profiling of the infertile male》。配套论文《Genetic and epigenetic profiling of the infertile male》发表于 PLOS ONE（2019），DOI：10.1371/journal.pone.0214275。源站首次发布：2019-03-21。

【数据内容】

源站原始描述：Evaluation of reproductive quality of spermatozoa by standard semen analysis is often inadequate to predict ART outcome. Men may be prone to meiotic error and have higher proportion of spermatozoa with fragmented chromatin, capable of affecting the conceptus'' health. In men with unexplained infertility, supplementary tests may be pivotal to gain insight into the paternal contribution to the zygotic genome. A total of 113 consenting men were included in the study, with an additional 5 donor speci…

【数据结构与技术规格】

文件数 3 个，合计 432.96 KB。pone.0214275.s001.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，20.60 KB。pone.0214275.s002.tif：image/tiff，91.45 KB。pone.0214275.s003.tif：image/tiff，320.91 KB。数据集 DOI：10.1371/journal.pone.0214275。

【主题与分类】

源站学科分类：Medicine、Cell Biology、Genetics、Molecular Biology、Biological Sciences not elsewhere classified、Developmental Biology。主题标签：17 ICSI cycles、pregnancy loss、NGS、pregnancy rate、Clinical pregnancy rate、DNA repair genes、APLF、CYB 5R ERCC 4、5 donor specimens、RNA。

【适用方向】

源站学科分类标注为 Medicine、Cell Biology、Genetics、Molecular Biology、Biological Sciences not elsewhere classified、Developmental Biology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Genetic_and_epigenetic_profiling_of_the_infertile_male/7876874

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Cheung, Stephanie; Parrella, Alessandra; Rosenwaks, Zev; D. Palermo, Gianpiero (2019). Genetic and epigenetic profiling of the infertile male. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。