染色体不稳定性、端粒长度和端粒维持与微卫星稳定直肠癌的相关性：直肠癌的分子亚类

资源简介

染色体不稳定性、端粒长度和端粒维持与微卫星稳定直肠癌的相关性：直肠癌的分子亚类

【数据集背景】

本数据集源站标题为《Correlation of Chromosomal Instability, Telomere Length and Telomere Maintenance in Microsatellite Stable Rectal Cancer: A Molecular Subclass of Rectal Cancer》。配套论文《Correlation of Chromosomal Instability, Telomere Length and Telomere Maintenance in Microsatellite Stable Rectal Cancer: A Molecular Subclass of Rectal Cancer》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0080015。源站首次发布：2013-11-21。

【数据内容】

源站原始描述：Introduction Colorectal cancer (CRC) tumor DNA is characterized by chromosomal damage termed chromosomal instability (CIN) and excessively shortened telomeres. Up to 80% of CRC is microsatellite stable (MSS) and is historically considered to be chromosomally unstable (CIN+). However, tumor phenotyping depicts some MSS CRC with little or no genetic changes, thus being chromosomally stable (CIN-). MSS CIN- tumors have not been assessed for telomere attrition. Experimental Design MSS rectal cancers…

【数据结构与技术规格】

文件数 2 个，合计 1.66 MB。Figure_S1.tif：image/tiff，825.66 KB。Figure_S2.tif：image/tiff，836.79 KB。数据集 DOI：10.1371/journal.pone.0080015。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：chromosomal、telomere、microsatellite、rectal、molecular、subclass。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Correlation_of_Chromosomal_Instability_Telomere_Length_and_Telomere_Maintenance_in_Microsatellite_Stable_Rectal_Cancer_A_Molecular_Subclass_of_Rectal_Cancer_/859681

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：A. Boardman, Lisa; A. Johnson, Ruth; B. Viker, Kimberly; A. Hafner, Kari; B. Jenkins, Robert; L. Riegert-Johnson, Douglas; et al. (2016). Correlation of Chromosomal Instability, Telomere Length and Telomere Maintenance in Microsatellite Stable Rectal Cancer: A Molecular Subclass of Rectal Cancer. PL…

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。