调节性CD4 T细胞在自身免疫性肝炎小鼠模型中维持耐受性的作用

资源简介

调节性CD4 T细胞在自身免疫性肝炎小鼠模型中维持耐受性的作用

【数据集背景】

本数据集源站标题为《The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis》。配套论文《The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0143715。源站首次发布：2015-11-24。

【数据内容】

源站原始描述：Background The role of regulatory CD4 T cells (Treg) in immune-mediated liver disease is still under debate. It remains disputed whether Treg suppress T cell-mediated hepatitis in vivo and whether hepatic regulatory T cells are functional in patients with autoimmune hepatitis. Methods We used TF-OVA mice, which express ovalbumin in hepatocytes, to investigate the impact of Treg in a model of autoimmune hepatitis. Treg isolated from inflamed livers of TF-OVA mice were tested for their functionali…

【数据结构与技术规格】

文件数 4 个，合计 140.95 KB。S1_Dataset.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，12.45 KB。S2_Dataset.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，39.72 KB。S3_Dataset.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，44.81 KB。数据集 DOI：10.1371/journal.pone.0143715。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：regulatory t cells、CD 4 T cells、cell population、tolerogenic milieu、hepatitis、Autoimmune Hepatitis BackgroundThe role、Treg.ConclusionOur data、t cells、Regulatory CD 4 T Cells、Mouse Model。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_The_Role_of_Regulatory_CD4_T_Cells_in_Maintaining_Tolerance_in_a_Mouse_Model_of_Autoimmune_Hepatitis_/1611606

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：an Haack, Ira; Derkow, Katja; Riehn, Mathias; Rentinck, Marc-Nicolas; A. Kühl, Anja; Lehnardt, Seija; et al. (2016). The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。