卵圆孔未闭装置封堵术——是时候更新指南了吗？

数据集获取（Figshare）

• 源站标题：Device Closure of Patent Foramen Ovale—Is it Time to Update the Guidelines?
• DOI：10.6084/m9.figshare.7464383
• 发布日期：2019-02-04
• 文件数：7 个
• 文件总体积：852.02 KB
• 源站页面：https://tandf.figshare.com/articles/dataset/Device_Closure_of_Patent_Foramen_Ovale_Is_it_Time_to_Update_Guidelines_/7464383

命令行下载

curl -L -o "Supplementary Figure1 300.tif" "https://ndownloader.figshare.com/files/13823522"
curl -L -o "Supplementary Figure2 300.tif" "https://ndownloader.figshare.com/files/13823525"
curl -L -o "Supplementary Figure3 300.tif" "https://ndownloader.figshare.com/files/13823528"
curl -L -o "Supplementary Figure4 300.tif" "https://ndownloader.figshare.com/files/13823531"
curl -L -o "Supplementary Figure5 300.tif" "https://ndownloader.figshare.com/files/13823534"
curl -L -o "Supplementary Figure6 300.tif" "https://ndownloader.figshare.com/files/13823537"
curl -L -o "Suppplementary Figure7 300.tif" "https://ndownloader.figshare.com/files/13823540"

文件清单

• Supplementary Figure1 300.tif（136.02 KB）
• Supplementary Figure2 300.tif（191.69 KB）
• Supplementary Figure3 300.tif（246.42 KB）
• Supplementary Figure4 300.tif（66.50 KB）
• Supplementary Figure5 300.tif（75.69 KB）
• Supplementary Figure6 300.tif（70.80 KB）
• Suppplementary Figure7 300.tif（64.90 KB）

文件总体积 852.02 KB（源站 API 实测）。

数据说明

Background: The current American Association of Neurology guidelines do not recommend patent foramen ovale (PFO) closure for prevention of cryptogenic strokes, however recent findings from randomized control trials (RCT) have challenged this recommendation. We performed a comprehensive analysis of RCTs available to date to compare PFO closure to medical therapy in patients with cryptogenic stroke.
Methods: Five databases were analyzed including EMBASE, PubMed, Cochrane, Scopus and Web-of-Science from January 2000 to September 2018. We included RCTs comparing device closure of PFO versus medical therapy in patients with cryptogenic stroke. Heterogeneity was determined using Cochrane’s Q statistics. A random effects model was used.
Results: Six randomized controlled trials and 3,560 patients were included in the analysis. Mean follow-up was 47 ± 19 months. Device closure was associated with a 42% reduction in recurrent embolic strokes when compared to medical therapy (risk ratio (RR): 0.58, 95% CI: 0.39–0.88, p = 0.009). This occurred despite atrial fibrillation occurring at a higher rate with device closure when compared to medical therapy (RR: 4.75, 95% CI: 2.35–9.60, p Conclusions: PFO device closure in appropriately selected patients with cryptogenic stroke is associated with a significant reduction in the risk of recurrent ischemic stroke. The increased incidence of atrial fibrillation associated with device closure appears to be transient. Long-term monitoring may be essential.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.7464383（source: https://tandf.figshare.com/articles/dataset/Device_Closure_of_Patent_Foramen_Ovale_Is_it_Time_to_Update_Guidelines_/7464383）。