代谢综合征对心肌主要代谢途径的稳健影响

资源简介

代谢综合征对心肌主要代谢途径的稳健影响

【数据集背景】

本数据集源站标题为《Robust effect of metabolic syndrome on major metabolic pathways in the myocardium》。配套论文《Robust effect of metabolic syndrome on major metabolic pathways in the myocardium》发表于 PLOS ONE（2019），DOI：10.1371/journal.pone.0225857。源站首次发布：2019-12-02。

【数据内容】

源站原始描述：Although the high-fat-diet-induced metabolic syndrome (MetS) is a precursor of human cardiac pathology, the myocardial metabolic state in MetS is far from clear. The discrepancies in metabolite handling between human and small animal models and the difficulties inherent in obtaining human tissue complicate the identification of the myocardium-specific metabolic response in patients. Here we use the large animal model of swine that develops the hallmark criteria of human MetS. Our comparative met…

【数据结构与技术规格】

文件数 4 个，合计 704.97 KB。pone.0225857.s001.pdf：application/pdf，127.35 KB。pone.0225857.s002.pdf：application/pdf，122.98 KB。pone.0225857.s003.pdf：application/pdf，251.27 KB。数据集 DOI：10.1371/journal.pone.0225857。

【主题与分类】

源站学科分类：Biochemistry、Cell Biology、Genetics、Molecular Biology、Physiology、Chemical Sciences not elsewhere classified。主题标签：pentose phosphate pathway、HBP、nonnegative matrix factorization、NMF、hexosamine biosynthetic pathway、expression、ketone body formation、CVD、MetS myocardium、glycogen。

【适用方向】

源站学科分类标注为 Biochemistry、Cell Biology、Genetics、Molecular Biology、Physiology、Chemical Sciences not elsewhere classified。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Robust_effect_of_metabolic_syndrome_on_major_metabolic_pathways_in_the_myocardium/11305490

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Karimi, Maryam; Pavlov, Vasile I.; Ziegler, Olivia; Sriram, Nivedita; Yoon, Se-Young; Agbortoko, Vahid; et al. (2019). Robust effect of metabolic syndrome on major metabolic pathways in the myocardium. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。