模拟长QT综合征中组织和突变特异性电生理效应：Purkinje纤维的作用

资源简介

模拟长QT综合征中组织和突变特异性电生理效应：Purkinje纤维的作用

【数据集背景】

本数据集源站标题为《Modeling Tissue- and Mutation- Specific Electrophysiological Effects in the Long QT Syndrome: Role of the Purkinje Fiber》。配套论文《Modeling Tissue- and Mutation- Specific Electrophysiological Effects in the Long QT Syndrome: Role of the Purkinje Fiber》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0097720。源站首次发布：2014-06-03。

【数据内容】

源站原始描述：Congenital long QT syndrome is a heritable family of arrhythmias caused by mutations in 13 genes encoding ion channel complex proteins. Mounting evidence has implicated the Purkinje fiber network in the genesis of ventricular arrhythmias. In this study, we explore the hypothesis that long QT mutations can demonstrate different phenotypes depending on the tissue type of expression. Using computational models of the human ventricular myocyte and the Purkinje fiber cell, the biophysical alteration…

【数据结构与技术规格】

文件数 2 个，合计 643.08 KB。File_S1.doc：application/msword，622.08 KB。Source_Code_S1.zip：application/zip，21.00 KB。数据集 DOI：10.1371/journal.pone.0097720。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：physiology、electrophysiology、Computer modeling、cardiology、Cardiovascular diseases、arrhythmia、tissue-、mutation-、electrophysiological、qt。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Modeling_Tissue_and_Mutation_Specific_Electrophysiological_Effects_in_the_Long_QT_Syndrome_Role_of_the_Purkinje_Fiber_/1045338

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Iyer, Vivek; J. Sampson, Kevin; S. Kass, Robert (2016). Modeling Tissue- and Mutation- Specific Electrophysiological Effects in the Long QT Syndrome: Role of the Purkinje Fiber. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。