成纤维细胞生长因子受体1信号在成年心肌细胞中增加收缩力并导致肥厚型心肌病

资源简介

成纤维细胞生长因子受体1信号在成年心肌细胞中增加收缩力并导致肥厚型心肌病

【数据集背景】

本数据集源站标题为《Fibroblast Growth Factor Receptor 1 Signaling in Adult Cardiomyocytes Increases Contractility and Results in a Hypertrophic Cardiomyopathy》。配套论文《Fibroblast Growth Factor Receptor 1 Signaling in Adult Cardiomyocytes Increases Contractility and Results in a Hypertrophic Cardiomyopathy》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0082979。源站首次发布：2013-12-11。

【数据内容】

源站原始描述：Fibroblast growth factors (FGFs) and their receptors are highly conserved signaling molecules that have been implicated in postnatal cardiac remodeling. However, it is not known whether cardiomyocyte-expressed FGF receptors are necessary or sufficient for ventricular remodeling in the adult heart. To determine whether cardiomyocytes were competent to respond to an activated FGF receptor, and to determine if this signal would result in the development of hypertrophy, we engineered a doxycycline (…

【数据结构与技术规格】

文件数 2 个，合计 9.56 MB。File_S1.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，937.44 KB。数据集 DOI：10.1371/journal.pone.0082979。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：receptor、cardiomyocytes、contractility、hypertrophic。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Fibroblast_Growth_Factor_Receptor_1_Signaling_in_Adult_Cardiomyocytes_Increases_Contractility_and_Results_in_a_Hypertrophic_Cardiomyopathy_/874791

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：N. Cilvik, Sarah; I. Wang, Joy; J. Lavine, Kory; Uchida, Keita; Castro, Angela; M. Gierasch, Carolyn; et al. (2016). Fibroblast Growth Factor Receptor 1 Signaling in Adult Cardiomyocytes Increases Contractility and Results in a Hypertrophic Cardiomyopathy. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。