DNA损伤易感性作为非综合征性唇腭裂的分子机制数据集

资源简介

DNA损伤易感性作为非综合征性唇腭裂的分子机制数据集

【数据集背景】

本数据集源站标题为《Susceptibility to DNA Damage as a Molecular Mechanism for Non-Syndromic Cleft Lip and Palate》。配套论文《Susceptibility to DNA Damage as a Molecular Mechanism for Non-Syndromic Cleft Lip and Palate》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0065677。源站首次发布：2013-06-12。

【数据内容】

源站原始描述：Non-syndromic cleft lip/palate (NSCL/P) is a complex, frequent congenital malformation, determined by the interplay between genetic and environmental factors during embryonic development. Previous findings have appointed an aetiological overlap between NSCL/P and cancer, and alterations in similar biological pathways may underpin both conditions. Here, using a combination of transcriptomic profiling and functional approaches, we report that NSCL/P dental pulp stem cells exhibit dysregulation of…

【数据结构与技术规格】

文件数 9 个，合计 3.90 MB。Figure_S1.tif：image/tiff，426.26 KB。Figure_S2.tif：image/tiff，160.19 KB。Figure_S3.tif：image/tiff，3.04 MB。数据集 DOI：10.1371/journal.pone.0065677。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：Biochemistry、Nucleic acids、dna、DNA repair、developmental biology、morphogenesis、Birth defects、stem cells、genetics、Molecular genetics。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Susceptibility_to_DNA_Damage_as_a_Molecular_Mechanism_for_Non_Syndromic_Cleft_Lip_and_Palate_/718078

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Shigeru Kobayashi, Gerson; Alvizi, Lucas; Yumi Sunaga, Daniele; Francis-West, Philippa; Kuta, Anna; Vinícius Pimenta Almada, Bruno; et al. (2016). Susceptibility to DNA Damage as a Molecular Mechanism for Non-Syndromic Cleft Lip and Palate. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-04，引用时请注意版本时效。