含Capparis sepiaria植物提取物的海藻酸钠/羧甲基纤维素凝胶制剂用于伤口愈合

数据集获取（Figshare）

• 源站标题：Sodium alginate/carboxymethylcellulose gel formulations containing <i>Capparis sepieria</i> plant extract for wound healing
• DOI：10.6084/m9.figshare.27677978.v1
• 发布日期：2024-11-12
• 文件数：2 个
• 文件总体积：2.09 MB
• 源站页面：https://tandf.figshare.com/articles/dataset/Sodium_alginate_carboxymethylcellulose_gel_formulations_containing_i_Capparis_sepieria_i_plant_extract_for_wound_healing/27677978

命令行下载

curl -L -o "Supp Figure 1 new.tif" "https://ndownloader.figshare.com/files/50380268"
curl -L -o "Supp Figure 2.pdf" "https://ndownloader.figshare.com/files/50380271"

文件清单

• Supp Figure 1 new.tif（2.04 MB）
• Supp Figure 2.pdf（45.31 KB）

文件总体积 2.09 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Aim: Using appropriate wound dressings is crucial when treating burn wounds to promote accelerated healing.
Materials & methods: Sodium alginate (SA)-based gels containing Carboxymethyl cellulose (CMC) and Pluronic F127 were prepared. The formulations. SA/CMC/Carbopol and SA/CMC/PluronicF127 were loaded with aqueous root extract of Capparis sepiaria. The formulations were characterized using appropriate techniques.
Results: The gels’’ viscosity was in the range of 676.33 ± 121.76 to 20.00 ± 9.78 cP and in vitro whole blood kinetics showed their capability to induce a faster clotting rate. They also supported high cell viability of 80% with cellular migration and proliferation. Their antibacterial activity was significant against most bacteria strains used in the study.
Conclusion: The gels’’ distinct features reveal their potential application as wound dressings for burn wounds.
Burn wounds are difficult to treat when invaded by microbes. Capparis sepiaria plant extract was loaded into gels. The gel formulations were non-toxic, with good antibacterial effects. These features are useful for the treatment of burn wounds.
SA/CMC/Carbopol and SA/CMC/PluronicF127 gels loaded with Capparis sepiaria are potential topical dressings for burn wounds.
SA/CMC/Carbopol and SA/CMC/PluronicF127 gels were prepared from sodium alginate, Pluronic F127, Carbopol and Carboxymethylcellulose and loaded with Capparis sepiaria plant extract as promising wound dressings.
The gel formulations displayed a non-Newtonian flow, revealing high spreadability and potential uniform distribution when administered topically on the skin surface. These features are appropriate for improving therapeutic efficacy and patient compliance.
All the gel formulations displayed good antibacterial efficacy against the gram-negative and gram-positive bacteria. However, SA/CMC/Carbopol gels displayed a significantly more antibacterial effect than the SA/CMC/Pluronic F127 gels and the reason is not fully known and requires further studies.
All the prepared gels displayed lower absorbance than Whole blood and plant extract, indicating their capability to control bleeding. However, gels TG6, TG7 and TG8 dis

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.27677978.v1（source: https://tandf.figshare.com/articles/dataset/Sodium_alginate_carboxymethylcellulose_gel_formulations_containing_i_Capparis_sepieria_i_plant_extract_for_wound_healing/27677978）。