miR-27b抑制小鼠间充质干细胞向烧伤边缘迁移并通过沉默SDF-1α延长伤口修复

资源简介

miR-27b抑制小鼠间充质干细胞向烧伤边缘迁移并通过沉默SDF-1α延长伤口修复

【数据集背景】

本数据集源站标题为《miR-27b Represses Migration of Mouse MSCs to Burned Margins and Prolongs Wound Repair through Silencing SDF-1a》。配套论文《miR-27b Represses Migration of Mouse MSCs to Burned Margins and Prolongs Wound Repair through Silencing SDF-1a》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0068972。源站首次发布：2013-07-22。

【数据内容】

源站原始描述：Background Interactions between stromal cell-derived factor-1α (SDF-1α) and its cognate receptor CXCR4 are crucial for the recruitment of mesenchymal stem cells (MSCs) from bone marrow (BM) reservoirs to damaged tissues for repair during alarm situations. MicroRNAs are differentially expressed in stem cell niches, suggesting a specialized role in stem cell regulation. Here, we gain insight into the molecular mechanisms involved in regulating SDF-1α. Methods MSCs from green fluorescent protein tr…

【数据结构与技术规格】

文件数 2 个，合计 5.48 MB。Figure_S1.tif：image/tiff，4.37 MB。Figure_S2.tif：image/tiff，1.11 MB。数据集 DOI：10.1371/journal.pone.0068972。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：Biochemistry、Nucleic acids、rna、Computational biology、microarrays、developmental biology、stem cells、mesenchymal stem cells、genetics、gene expression。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_miR_27b_Represses_Migration_of_Mouse_MSCs_to_Burned_Margins_and_Prolongs_Wound_Repair_through_Silencing_SDF_1a_/749924

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Lü, Mu-Han; Hu, Chang-Jiang; Chen, Ling; Peng, Xi; Chen, Jian; Hu, Jiong-Yu; et al. (2016). miR-27b Represses Migration of Mouse MSCs to Burned Margins and Prolongs Wound Repair through Silencing SDF-1a. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。