PGE2含量降低减少MMP-1活性并因此增加人类静脉曲张胶原密度

资源简介

PGE2含量降低减少MMP-1活性并因此增加人类静脉曲张胶原密度

【数据集背景】

本数据集源站标题为《Decreased PGE2 Content Reduces MMP-1 Activity and Consequently Increases Collagen Density in Human Varicose Vein》。配套论文《Decreased PGE2 Content Reduces MMP-1 Activity and Consequently Increases Collagen Density in Human Varicose Vein》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0088021。源站首次发布：2014-02-05。

【数据内容】

源站原始描述：Varicose veins are elongated and dilated saphenous veins. Despite the high prevalence of this disease, its pathogenesis remains unclear. Aims In this study, we investigated the control of matrix metalloproteinases (MMPs) expression by prostaglandin (PG)E2 during the vascular wall remodeling of human varicose veins. Methods and Results Varicose (small (SDv) and large diameter (LDv)) and healthy saphenous veins (SV) were obtained after surgery. Microsomal and cytosolic PGE-synthases (mPGES and cPG…

【数据结构与技术规格】

文件数 6 个，合计 16.02 MB。Figure_S1.tif：image/tiff，44.62 KB。Figure_S2.tif：image/tiff，238.54 KB。Figure_S3.tif：image/tiff，424.63 KB。数据集 DOI：10.1371/journal.pone.0088021。

【主题与分类】

源站学科分类：Biological Sciences、Medicine。主题标签：Anatomy and physiology、cardiovascular system、Circulatory physiology、Biochemistry、lipids、Lipid mediators、Lipid metabolism、metabolism、cardiovascular、Peripheral vascular diseases。

【适用方向】

源站学科分类标注为 Biological Sciences、Medicine。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Decreased_PGE_2_Content_Reduces_MMP_1_Activity_and_Consequently_Increases_Collagen_Density_in_Human_Varicose_Vein/927791

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Gomez, Ingrid; Benyahia, Chabha; Louedec, Liliane; Leséche, Guy; Jacob, Marie-Paule; Longrois, Dan; et al. (2016). Decreased PGE2 Content Reduces MMP-1 Activity and Consequently Increases Collagen Density in Human Varicose Vein. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。