金属对金属髋关节植入物中钴的耳毒性潜力：患者报告的听觉、前庭和一般神经学结果的初步研究
一份关于金属对金属髋关节植入物患者钴耳毒性的问卷数据，评估听觉、前庭和神经学症状。
基本信息
资源简介
金属对金属髋关节植入物中钴的耳毒性潜力：患者报告的听觉、前庭和一般神经学结果的初步研究
【一句话概览】
本数据集是 figshare 公开的文本数据集，收录 3 个文件、合计 9.10 MB，主题涵盖 Metal-on-metal implant、cobalt、ototoxicity、neurotoxicity，可用于医学自然语言处理（实体识别、信息抽取等），CC BY-NC-ND 4.0 许可开放获取。
【数据集背景】
本数据集源站标题为《The ototoxic potential of cobalt from metal-on-metal hip implants: a pilot study on the patient-reported auditory, vestibular, and general neurological outcome》。配套论文《The ototoxic potential of cobalt from metal-on-metal hip implants: a pilot study on the patient-reported auditory, vestibular, and general neurological outcome》发表于 International Journal of Audiology（2020），DOI：10.1080/14992027.2020.1789922。项目资助方：L.L. has received funding from the Special Research Fund of Ghent University (BOF) [grant no. BOF15/DOC/330] and is currently receiving funding from the Research Foundation Flanders (FWO) [grant no. FWO/17/ASP/143], as a predoctoral research fellow.。源站首次发布：2020-08-24。
【数据内容】
源站原始描述：This study aimed to systematically investigate the ototoxic potential of cobalt in patients with a metal-on-metal (MoM) hip implant, using objective auditory and vestibular assessments and a questionnaire. The results of the objective evaluation were published previously, whereas the current study focused on the questionnaire outcome and its relationship to the blood cobalt level. Design and study sample: Twenty patients (33–65 years) with a primary MoM hip implant and 20 non-implanted control s…
中文译文（机器翻译，仅供快速理解，请以原文为准）：本研究旨在采用客观听觉和前庭评估及问卷，系统研究金属对金属（MoM）髋关节植入物患者的钴耳毒性潜力。客观评估的结果已于先前发表，而本研究侧重于问卷结果及其与血钴水平的关系。 设计与研究样本：20例（33–65岁）植入初次MoM髋关节假体的患者和20名未植入对照受试者，按年龄、性别和噪声暴露匹配，接受问卷以评估若干听力和平衡症状（第1部分）及一般神经学问题（第2部分）。 关于第1部分，MoM患者组总体上听觉相关症状的比例（p = 0.022）和耳鸣（p = 0.047）显著更高，而听觉过敏、聆听努力增加和言语理解能力下降方面未发现组间差异。关于第2部分，未检测到显著的组间差异。在MoM患者组内，根据血钴水平划分的低暴露和高暴露亚组之间，问卷结果无显著差异。 与我们先前的研究一致，这些结果可能提示钴诱导的听觉系统损伤，尽管缺乏明确的剂量-反应关系。
【数据结构与技术规格】
文件数 3 个，合计 9.10 MB。iija_a_1789922_sm5688.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，3.03 MB。iija_a_1789922_sm5686.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，3.04 MB。iija_a_1789922_sm5685.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，3.03 MB。数据集 DOI：10.6084/m9.figshare.12850577.v1。
【主题与分类】
源站学科分类：Space Science、Medicine、Cell Biology、Immunology、Biological Sciences not elsewhere classified、Cancer。主题标签：Metal-on-metal implant、cobalt、ototoxicity、neurotoxicity。
【适用方向】
文本类数据可用于医学自然语言处理，如命名实体识别、信息抽取与文本分类。
【获取与许可】
源站页面：https://tandf.figshare.com/articles/dataset/The_ototoxic_potential_of_cobalt_from_metal-on-metal_hip_implants_a_pilot_study_on_the_patient-reported_auditory_vestibular_and_general_neurological_outcome/12850577
使用许可：CC BY-NC-ND 4.0（https://creativecommons.org/licenses/by-nc-nd/4.0/）。
规范引用：The ototoxic potential of cobalt from metal-on-metal hip implants: a pilot study on the patient-reported auditory, vestibular, and general neurological outcome. Taylor & Francis. Leyssens, Laura; Vinck, Bart; Van Der Straeten, Catherine; Dhooge, Ingeborg; Wuyts, Floris L.; Maes, Leen K
【使用注意】
· 源站最后修改于 2023-05-31，引用时请注意版本时效。
下载信息
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使用方式
数据集获取（Figshare）
- 源站标题：The ototoxic potential of cobalt from metal-on-metal hip implants: a pilot study on the patient-reported auditory, vestibular, and general neurological outcome
- DOI：10.6084/m9.figshare.12850577.v1
- 发布日期：2020-08-24
- 文件数：3 个
- 文件总体积：9.10 MB
- 源站页面：https://tandf.figshare.com/articles/dataset/The_ototoxic_potential_of_cobalt_from_metal-on-metal_hip_implants_a_pilot_study_on_the_patient-reported_auditory_vestibular_and_general_neurological_outcome/12850577
命令行下载
curl -L -o "iija_a_1789922_sm5688.docx" "https://ndownloader.figshare.com/files/24412430"
curl -L -o "iija_a_1789922_sm5686.docx" "https://ndownloader.figshare.com/files/24412433"
curl -L -o "iija_a_1789922_sm5685.docx" "https://ndownloader.figshare.com/files/24412436"
文件清单
iija_a_1789922_sm5688.docx（3.03 MB）iija_a_1789922_sm5686.docx（3.04 MB）iija_a_1789922_sm5685.docx（3.03 MB）
文件总体积 9.10 MB（源站 API 实测）。
数据说明
This study aimed to systematically investigate the ototoxic potential of cobalt in patients with a metal-on-metal (MoM) hip implant, using objective auditory and vestibular assessments and a questionnaire. The results of the objective evaluation were published previously, whereas the current study focused on the questionnaire outcome and its relationship to the blood cobalt level.
Design and study sample: Twenty patients (33–65 years) with a primary MoM hip implant and 20 non-implanted control subjects, matched for age, gender, and noise exposure, received a questionnaire to evaluate the presence of several hearing and balance symptoms (part 1) and general neurological issues (part 2).
Concerning part 1, the proportion of auditory-related symptoms in general (p = 0.022) and tinnitus (p = 0.047) was significantly higher in the MoM patient group, whereas no group difference was found for hyperacusis, increased listening effort, and decreased speech understanding. Concerning part 2, no significant group differences were detected. Within the MoM patient group, the questionnaire outcome was not significantly different between the low-exposure and high-exposure subgroups according to the blood Co level.
In line with our previous study, these results potentially imply Co-induced impairment to the auditory system, despite the lack of a clear dose–response relationship.
许可
CC BY-NC-ND 4.0
引用
学术使用请引用 DOI 10.6084/m9.figshare.12850577.v1（source: https://tandf.figshare.com/articles/dataset/The_ototoxic_potential_of_cobalt_from_metal-on-metal_hip_implants_a_pilot_study_on_the_patient-reported_auditory_vestibular_and_general_neurological_outcome/12850577）。
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