植入式渗透转运装置减轻严重挫伤性脊髓损伤后水肿的数据表1

OTS装置减轻大鼠严重脊髓挫伤后水肿的实验数据,包括4小时和28天的水肿测量结果。

NIAID Data Ecosystem
浏览 17
表格spinal cord injuryedemasevere contusionimplantable devicemembrane separationsosmotic transport device (OTD)
Data_Sheet_1_Implantable Osmotic Transport Device Can Reduce Edema After Severe Contusion Spinal Cord Injury.docx

基本信息

模态
表格
大小
0.001459933 GB
许可
CC BY 4.0
创建/更新时间
2026-10-08
版本
v1

资源简介

植入式渗透转运装置减轻严重挫伤性脊髓损伤后水肿的数据表1

【一句话概览】

本数据集是 figshare 公开的结构化表格数据集,收录 1 个文件、合计 1.46 MB,主题涵盖 spinal cord injury、edema、severe contusion、implantable device、membrane separations,可用于统计建模、特征工程与队列分析,CC BY 4.0 许可开放获取。

【数据集背景】

本数据集源站标题为《Data_Sheet_1_Implantable Osmotic Transport Device Can Reduce Edema After Severe Contusion Spinal Cord Injury.docx》。配套论文《Effect of combined treatment with melatonin and methylprednisolone on neurological recovery after experimental spinal cord injury》发表于 European Spine Journal(2004),DOI:10.1007/s00586-003-0550-y。源站首次发布:2020-07-10。

【数据内容】

源站原始描述:Recent findings from the ISCoPe study indicate that, after severe contusion to the spinal cord, edema originating in the spinal cord accumulates and compresses the tissue against the surrounding dura mater, despite decompressive laminectomy. It is hypothesized that this compression results in restricted flow of cerebrospinal fluid (CSF) in the subarachnoid space and central canal and ultimately collapses local vasculature, exacerbating ischemia and secondary injury. Here we developed a surgicall…

【数据结构与技术规格】

文件数 1 个,合计 1.46 MB。Data_Sheet_1_Implantable Osmotic Transport Device Can Reduce Edema After Severe Contusion Spinal Cord Injury.docx:application/vnd.openxmlformats-officedocument.wordprocessingml.document,1.46 MB。数据集 DOI:10.3389/fbioe.2020.00806.s001。

【主题与分类】

源站学科分类:Bioprocessing, Bioproduction and Bioproducts、Industrial Biotechnology Diagnostics (incl. Biosensors)、Industrial Microbiology (incl. Biofeedstocks)、Industrial Molecular Engineering of Nucleic Acids and Proteins、Industrial Biotechnology not elsewhere classified、Medical Biotechnology Diagnostics (incl. Biosensors)。主题标签:spinal cord injury、edema、severe contusion、implantable device、membrane separations、osmotic transport device (OTD)。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面:https://frontiersin.figshare.com/articles/dataset/Data_Sheet_1_Implantable_Osmotic_Transport_Device_Can_Reduce_Edema_After_Severe_Contusion_Spinal_Cord_Injury_docx/12639371

使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。

规范引用:Hale, Christopher; Yonan, Jennifer; Batarseh, Ramsey; Chaar, Roman; Jonak, Carrie R.; Ge, Shaokui; et al. (2020). Data_Sheet_1_Implantable Osmotic Transport Device Can Reduce Edema After Severe Contusion Spinal Cord Injury.docx. Frontiers. Dataset

【使用注意】

· 源站最后修改于 2023-06-01,引用时请注意版本时效。

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下载信息

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需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。

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当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。

使用方式

数据集获取(Figshare)

命令行下载

curl -L -o "Data_Sheet_1_Implantable Osmotic Transport Device Can Reduce Edema After Severe Contusion Spinal Cord Injury.docx" "https://ndownloader.figshare.com/files/23770019"

文件清单

  • Data_Sheet_1_Implantable Osmotic Transport Device Can Reduce Edema After Severe Contusion Spinal Cord Injury.docx(1.46 MB)

文件总体积 1.46 MB(源站 API 实测)。

数据说明

Recent findings from the ISCoPe study indicate that, after severe contusion to the spinal cord, edema originating in the spinal cord accumulates and compresses the tissue against the surrounding dura mater, despite decompressive laminectomy. It is hypothesized that this compression results in restricted flow of cerebrospinal fluid (CSF) in the subarachnoid space and central canal and ultimately collapses local vasculature, exacerbating ischemia and secondary injury. Here we developed a surgically mounted osmotic transport device (OTD) that rests on the dura and can osmotically remove excess fluid at the injury site. Tests were performed in 4-h studies immediately following severe (250 kD) contusion at T8 in rats using the OTD. A 3-h treatment with the OTD after 1-h post injury significantly reduced spinal cord edema compared to injured controls. A first approximation mathematical interpretation implies that this modest reduction in edema may be significant enough to relieve compression of local vasculature and restore flow of CSF in the region. In addition, we determined the progression of edema up to 28 days after insult in the rat for the same injury model. Results showed peak edema at 72 h. These preliminary results suggest that incorporating the OTD to operate continuously at the site of injury throughout the critical period of edema progression, the device may significantly improve recovery following contusion spinal cord injury.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.3389/fbioe.2020.00806.s001(source: https://frontiersin.figshare.com/articles/dataset/Data_Sheet_1_Implantable_Osmotic_Transport_Device_Can_Reduce_Edema_After_Severe_Contusion_Spinal_Cord_Injury_docx/12639371)。

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