比较重复经颅磁刺激与抗抑郁药物在新诊断重度抑郁症患者首次治疗失败后的成本效果分析——终身分析数据集

数据集获取（Figshare）

• 源站标题：Cost effectiveness analysis comparing repetitive transcranial magnetic stimulation to antidepressant medications after a first treatment failure for major depressive disorder in newly diagnosed patients – A lifetime analysis
• DOI：10.1371/journal.pone.0186950
• 发布日期：2017-10-26
• 文件数：27 个
• 文件总体积：1.96 MB
• 源站页面：https://plos.figshare.com/articles/dataset/Cost_effectiveness_analysis_comparing_repetitive_transcranial_magnetic_stimulation_to_antidepressant_medications_after_a_first_treatment_failure_for_major_depressive_disorder_in_newly_diagnosed_patients_A_lifetime_analysis/5542372

命令行下载

curl -L -o "S1 Fig.pdf" "https://ndownloader.figshare.com/files/9601612"
curl -L -o "S2 Fig.pdf" "https://ndownloader.figshare.com/files/9601624"
curl -L -o "S3 Fig.pdf" "https://ndownloader.figshare.com/files/9601666"
curl -L -o "S4 Fig.pdf" "https://ndownloader.figshare.com/files/9601678"
curl -L -o "S5 Fig.pdf" "https://ndownloader.figshare.com/files/9601711"
curl -L -o "S6 Fig.pdf" "https://ndownloader.figshare.com/files/9601759"
curl -L -o "S7 Fig.pdf" "https://ndownloader.figshare.com/files/9601777"
curl -L -o "S8 Fig.pdf" "https://ndownloader.figshare.com/files/9601801"

文件清单

• S1 Fig.pdf（62.06 KB）
• S2 Fig.pdf（133.94 KB）
• S3 Fig.pdf（133.53 KB）
• S4 Fig.pdf（130.58 KB）
• S5 Fig.pdf（124.33 KB）
• S6 Fig.pdf（81.88 KB）
• S7 Fig.pdf（83.75 KB）
• S8 Fig.pdf（77.97 KB）
• S9 Fig.pdf（82.86 KB）
• S10 Fig.pdf（70.25 KB）
• S11 Fig.pdf（68.93 KB）
• S12 Fig.pdf（72.02 KB）
• S13 Fig.pdf（69.28 KB）
• S14 Fig.pdf（69.17 KB）
• S15 Fig.pdf（68.47 KB）
• S16 Fig.pdf（66.81 KB）
• S17 Fig.pdf（65.90 KB）
• S18 Fig.pdf（66.05 KB）
• S19 Fig.pdf（62.61 KB）
• S20 Fig.pdf（71.37 KB）

文件总体积 1.96 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Objective
Repetitive Transcranial Magnetic Stimulation (rTMS) commonly is used for the treatment of Major Depressive Disorder (MDD) after patients have failed to benefit from trials of multiple antidepressant medications. No analysis to date has examined the cost-effectiveness of rTMS used earlier in the course of treatment and over a patients’ lifetime.
Methods
We used lifetime Markov simulation modeling to compare the direct costs and quality adjusted life years (QALYs) of rTMS and medication therapy in patients with newly diagnosed MDD (ages 20–59) who had failed to benefit from one pharmacotherapy trial. Patients’ life expectancies, rates of response and remission, and quality of life outcomes were derived from the literature, and treatment costs were based upon published Medicare reimbursement data. Baseline costs, aggregate per year quality of life assessments (QALYs), Monte Carlo simulation, tornado analysis, assessment of dominance, and one way sensitivity analysis were also performed. The discount rate applied was 3%.
Results
Lifetime direct treatment costs, and QALYs identified rTMS as the dominant therapy compared to antidepressant medications (i.e., lower costs with better outcomes) in all age ranges, with costs/improved QALYs ranging from $2,952/0.32 (older patients) to $11,140/0.43 (younger patients). One-way sensitivity analysis demonstrated that the model was most sensitive to the input variables of cost per rTMS session, monthly prescription drug cost, and the number of rTMS sessions per year.
Conclusion
rTMS was identified as the dominant therapy compared to antidepressant medication trials over the life of the patient across the lifespan of adults with MDD, given current costs of treatment. These models support the use of rTMS after a single failed antidepressant medication trial versus further attempts at medication treatment in adults with MDD.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0186950（source: https://plos.figshare.com/articles/dataset/Cost_effectiveness_analysis_comparing_repetitive_transcranial_magnetic_stimulation_to_antidepressant_medications_after_a_first_treatment_failure_for_major_depressive_disorder_in_newly_diagnosed_patients_A_lifetime_analysis/5542372）。