如何选择多发性硬化症患者的初始治疗：基于病例的方法

数据集获取（Figshare）

• 源站标题：How to choose initial treatment in multiple sclerosis patients: a case-based approach
• DOI：10.6084/m9.figshare.20484464.v1
• 发布日期：2022-08-13
• 文件数：8 个
• 文件总体积：1.03 MB
• 源站页面：https://scielo.figshare.com/articles/dataset/How_to_choose_initial_treatment_in_multiple_sclerosis_patients_a_case-based_approach/20484464

命令行下载

curl -L -o "cfdd4ac6b7735dfaffb004cada04b6b702eccc17.jpg" "https://ndownloader.figshare.com/files/36666152"
curl -L -o "a6fd9f36f640b3b47470ab5a61ea5bb1db4e7e0a.jpg" "https://ndownloader.figshare.com/files/36666155"
curl -L -o "e7aaa13fe29369832290699a248ca0f53cff3f4d.jpg" "https://ndownloader.figshare.com/files/36666158"
curl -L -o "51f97c196a9772e677975012e6353d41fbc8fbbc.jpg" "https://ndownloader.figshare.com/files/36666161"
curl -L -o "44ebc57b509c29f496ed92fd02b8111d0c6ae36a.jpg" "https://ndownloader.figshare.com/files/36666164"
curl -L -o "74d7a52b7ffe14462b9dbe1c42824db11c289e36.jpg" "https://ndownloader.figshare.com/files/36666167"
curl -L -o "Table_1.xls" "https://ndownloader.figshare.com/files/36666170"
curl -L -o "Table_2.xls" "https://ndownloader.figshare.com/files/36666176"

文件清单

• cfdd4ac6b7735dfaffb004cada04b6b702eccc17.jpg（223.21 KB）
• a6fd9f36f640b3b47470ab5a61ea5bb1db4e7e0a.jpg（7.95 KB）
• e7aaa13fe29369832290699a248ca0f53cff3f4d.jpg（392.72 KB）
• 51f97c196a9772e677975012e6353d41fbc8fbbc.jpg（8.79 KB）
• 44ebc57b509c29f496ed92fd02b8111d0c6ae36a.jpg（371.77 KB）
• 74d7a52b7ffe14462b9dbe1c42824db11c289e36.jpg（7.59 KB）
• Table_1.xls（5.63 KB）
• Table_2.xls（9.73 KB）

文件总体积 1.03 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

ABSTRACT Background: Immunotherapy dramatically changed the natural history of multiple sclerosis (MS), which was classically associated with severe disability. Treatment strategies advocate that early control of disease activity is crucial to avoid progressive disability, and the use of high efficacy drugs may be beneficial, but safety is a concern. Choosing the disease-modifying therapy is challenging in clinical practice and should be further discussed. Objective: To discuss the state of art of selecting the initial therapy for relapsing MS patients. Methods: We used a case-based approach followed by clinical discussion, exploring therapeutic options in different MS settings. Results: We presented clinical cases profile compatible with the use of MS therapies, classified into moderate and high efficacy. In the moderate efficacy group, we discussed interferons, glatiramer acetate, teriflunomide and dimethyl fumarate, while in the high efficacy group we discussed fingolimod, cladribine, natalizumab, ocrelizumab, alemtuzumab and ofatumumab. Conclusion: Advances in MS treatment are remarkable. Strong evidence supports the use of early high efficacy therapy. However, biomarkers, clinical and radiologic prognostic factors, as well as patients’’ individual issues, should be valued and considered for a personalized treatment decision.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.20484464.v1（source: https://scielo.figshare.com/articles/dataset/How_to_choose_initial_treatment_in_multiple_sclerosis_patients_a_case-based_approach/20484464）。