急性分支动脉粥样硬化病静脉溶栓治疗研究数据

数据集获取（Figshare）

• 源站标题：Data_Sheet_2_Efficacy and Safety of Intravenous Thrombolysis on Acute Branch Atheromatous Disease: A Retrospective Case–Control Study.PDF
• DOI：10.3389/fneur.2020.00581.s002
• 发布日期：2020-07-07
• 文件数：1 个
• 文件总体积：123.03 KB
• 源站页面：https://frontiersin.figshare.com/articles/dataset/Data_Sheet_2_Efficacy_and_Safety_of_Intravenous_Thrombolysis_on_Acute_Branch_Atheromatous_Disease_A_Retrospective_Case_Control_Study_PDF/12617066

命令行下载

curl -L -o "Data_Sheet_2_Efficacy and Safety of Intravenous Thrombolysis on Acute Branch Atheromatous Disease: A Retrospective Case–Control Study.PDF" "https://ndownloader.figshare.com/files/23716319"

文件清单

• Data_Sheet_2_Efficacy and Safety of Intravenous Thrombolysis on Acute Branch Atheromatous Disease: A Retrospective Case–Control Study.PDF（123.03 KB）

文件总体积 123.03 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background and Objective: Branch atheromatous disease (BAD) is distinctive from large-artery atherosclerosis and small-vessel disease, which is single subcortical infarction caused by the occlusion of perforator’'s orifice. This study aimed to indicate whether intravenous thrombolysis (IVT) with alteplase could prevent early neurological deterioration (END) and improve functional outcome for patients with BAD within 4.5 h after symptom onset.
Methods: We retrospectively analyzed data collected from patients with BAD who were admitted to our hospital from January 2015 to August 2019. To investigate the efficacy and safety of IVT, subjects were classified into alteplase and control groups. A propensity score matching analysis was performed to control substantial heterogeneity of subgroup. The coprimary outcomes were END that is defined as an increase of ≥2 points in the National Institutes of Health Stroke Scale (NIHSS) score within 7 days after stroke, and favorable outcome at 3 months after stroke that defined by a score of 0–1 point on the modified Rankin scale (mRS).
Results: A total of 135 patients were eventually enrolled in this study (n = 51 for the alteplase group and n = 84 for the control group). Additionally, 42 pairs of subjects were successfully matched by propensity score matching. Intravenous alteplase within 4.5 h after stroke onset reduced the incidence of END [unadjusted odds ratio (OR), 3.32; 95% confidence interval (CI), 1.06–10.37] and improved the clinical outcome at 3 months after stroke, with more patients achieving favorable functional prognosis (mRS, 0–1 point; unadjusted OR, 0.25; 95% CI, 0.10–0.62). Patients in the alteplase group were more likely to be independent (mRS, 0–2 points) at 3 months after stroke (unadjusted OR, 0.33; 95% CI, 0.12–0.90). The rate of death or dependence (mRS, ≥4 points) in the alteplase group was also markedly lower than that in the control group (unadjusted OR, 4.06; 95% CI, 1.03–16.02).
Conclusion: Our findings indicated that intravenous thrombolysis may be a safe and effective therapy for patients with BAD.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.3389/fneur.2020.00581.s002（source: https://frontiersin.figshare.com/articles/dataset/Data_Sheet_2_Efficacy_and_Safety_of_Intravenous_Thrombolysis_on_Acute_Branch_Atheromatous_Disease_A_Retrospective_Case_Control_Study_PDF/12617066）。