美国耐药性局灶性癫痫患者的癫痫发作负担与医疗资源利用

数据集获取（Figshare）

• 源站标题：Seizure burden and healthcare resource utilization among people living with drug-resistant focal epilepsy in the United States
• DOI：10.6084/m9.figshare.26807859.v1
• 发布日期：2024-08-22
• 文件数：2 个
• 文件总体积：196.14 KB
• 源站页面：https://tandf.figshare.com/articles/dataset/Seizure_burden_and_healthcare_resource_utilization_among_people_living_with_drug-resistant_focal_epilepsy_in_the_United_States/26807859

命令行下载

curl -L -o "icmo_a_2396049_sm5967.docx" "https://ndownloader.figshare.com/files/48722894"
curl -L -o "icmo_a_2396049_sm5966.docx" "https://ndownloader.figshare.com/files/48722897"

文件清单

• icmo_a_2396049_sm5967.docx（64.98 KB）
• icmo_a_2396049_sm5966.docx（131.16 KB）

文件总体积 196.14 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

This study investigated clinical characteristics, burden of uncontrolled seizures, and seizure-related healthcare resource utilization (HRU) among individuals living with drug-resistant focal epilepsy (FE) in the United States (US).
Medical charts of adults with drug-resistant FE who initiated third-line (3 L) anti-seizure medication were extracted from clinical practices in the US (1/1/2013–1/31/2020). The index date, defined as the date of 3 L initiation, was used to indicate the emergence of drug resistance. Individuals on cenobamate were followed for any length of time from the index date. Demographic and clinical characteristics were analyzed descriptively. Primary clinical outcomes included seizure burden (i.e. change in seizure frequency and time to the first and second seizure events) and epilepsy-related HRU.
Overall, 189 neurologists/epileptologists contributed 345 charts of individuals living with drug-resistant FE (66% male; average age 24 years at diagnosis and 32 years at index date). 66% had ≥1 neurologic/neuropsychiatric comorbidity at baseline. Average monthly seizure rate decreased from 6.1 at baseline to 3.8 at follow-up; however, nearly half of individuals experienced worse/no change or only some improvement (Despite the availability of many anti-seizure medications in the US, people living with drug-resistant FE continue to experience multiple seizures per month and incur substantial healthcare resources. Novel pharmacotherapies may help individuals living with drug-resistant epilepsy achieve seizure freedom.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.26807859.v1（source: https://tandf.figshare.com/articles/dataset/Seizure_burden_and_healthcare_resource_utilization_among_people_living_with_drug-resistant_focal_epilepsy_in_the_United_States/26807859）。