LTA4H基因型与细菌性脑膜炎易感性相关但非预后关键决定因素

资源简介

LTA4H基因型与细菌性脑膜炎易感性相关但非预后关键决定因素

【数据集背景】

本数据集源站标题为《LTA4H Genotype Is Associated with Susceptibility to Bacterial Meningitis but Is Not a Critical Determinant of Outcome》。配套论文《LTA4H Genotype Is Associated with Susceptibility to Bacterial Meningitis but Is Not a Critical Determinant of Outcome》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0118789。源站首次发布：2015-03-23。

【数据内容】

源站原始描述：Adjunctive dexamethasone saves lives in the treatment of tuberculous meningitis but this response is influenced by the patient’s LTA4H genotype. Despite less certain benefit, adjunctive dexamethasone is also frequently used in the treatment of pyogenic bacterial meningitis, but the influence of LTA4H genotype on outcomes has not been previously investigated. We genotyped the LTA4H promoter region SNP (rs17525495) in 390 bacterial meningitis patients and 751 population controls. rs17525495 was as…

【数据结构与技术规格】

文件数 2 个，合计 36.46 KB。S1_Table.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，18.56 KB。S2_Table.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，17.90 KB。数据集 DOI：10.1371/journal.pone.0118789。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：disease severity、influence、ci、LTA 4H promoter region SNP、tuberculous meningitis、Critical Determinant、Outcome Adjunctive dexamethasone、rs 17525495、Bacterial meningitis、Dexamethasone treatment。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_LTA4H_Genotype_Is_Associated_with_Susceptibility_to_Bacterial_Meningitis_but_Is_Not_a_Critical_Determinant_of_Outcome/1350725

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：J. Dunstan, Sarah; Thi Bich Tram, Trinh; E. Thwaites, Guy; Thi Hong Chau, Tran; Hoan Phu, Nguyen; Tinh Hien, Tran; et al. (2016). LTA4H Genotype Is Associated with Susceptibility to Bacterial Meningitis but Is Not a Critical Determinant of Outcome. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。