小肠腺癌全外显子组体细胞突变特征数据集

资源简介

小肠腺癌全外显子组体细胞突变特征数据集

【数据集背景】

本数据集源站标题为《Exome-wide somatic mutation characterization of small bowel adenocarcinoma》。配套论文《Exome-wide somatic mutation characterization of small bowel adenocarcinoma》发表于 PLOS Genetics（2018），DOI：10.1371/journal.pgen.1007200。源站首次发布：2018-03-09。

【数据内容】

源站原始描述：Small bowel adenocarcinoma (SBA) is an aggressive disease with limited treatment options. Despite previous studies, its molecular genetic background has remained somewhat elusive. To comprehensively characterize the mutational landscape of this tumor type, and to identify possible targets of treatment, we conducted the first large exome sequencing study on a population-based set of SBA samples from all three small bowel segments. Archival tissue from 106 primary tumors with appropriate clinical…

【数据结构与技术规格】

文件数 15 个，合计 1.58 MB。pgen.1007200.s001.pdf：application/pdf，63.18 KB。pgen.1007200.s002.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，25.86 KB。pgen.1007200.s003.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，81.57 KB。数据集 DOI：10.1371/journal.pgen.1007200。

【主题与分类】

源站学科分类：Genetics、Molecular Biology、Chemical Sciences not elsewhere classified、Biological Sciences not elsewhere classified、Information Systems not elsewhere classified、Cancer。主题标签：ERBB、SMARCA、ARID、bowel segments、2A、SOX、KRAS、BRCA、APC、ACVR。

【适用方向】

源站学科分类标注为 Genetics、Molecular Biology、Chemical Sciences not elsewhere classified、Biological Sciences not elsewhere classified、Information Systems not elsewhere classified、Cancer。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Exome-wide_somatic_mutation_characterization_of_small_bowel_adenocarcinoma/5967298

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Hänninen, Ulrika A.; Katainen, Riku; Tanskanen, Tomas; Plaketti, Roosa-Maria; Laine, Riku; Hamberg, Jiri; et al. (2018). Exome-wide somatic mutation characterization of small bowel adenocarcinoma. PLOS Genetics. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。