SNP阵列核型分析揭示原发性骨髓纤维化中新型复发性20p13扩增

资源简介

SNP阵列核型分析揭示原发性骨髓纤维化中新型复发性20p13扩增

【数据集背景】

本数据集源站标题为《SNPs Array Karyotyping Reveals a Novel Recurrent 20p13 Amplification in Primary Myelofibrosis》。配套论文《SNPs Array Karyotyping Reveals a Novel Recurrent 20p13 Amplification in Primary Myelofibrosis》发表于 PLoS ONE（2011），DOI：10.1371/journal.pone.0027560。源站首次发布：2011-11-14。

【数据内容】

源站原始描述：The molecular pathogenesis of primary mielofibrosis (PMF) is still largely unknown. Recently, single-nucleotide polymorphism arrays (SNP-A) allowed for genome-wide profiling of copy-number alterations and acquired uniparental disomy (aUPD) at high-resolution. In this study we analyzed 20 PMF patients using the Genome-Wide Human SNP Array 6.0 in order to identify novel recurrent genomic abnormalities. We observed a complex karyotype in all cases, detecting all the previously reported lesions (del…

【数据结构与技术规格】

文件数 7 个，合计 3.98 MB。Figure_S1.tif：image/tiff，1.29 MB。Figure_S3.tif：image/tiff，572.94 KB。数据集 DOI：10.1371/journal.pone.0027560。

【主题与分类】

源站学科分类：Hematology、Biological Sciences、Genetics、Immunology、Evolutionary Biology。主题标签：snps、karyotyping、reveals、recurrent、20p13、amplification、myelofibrosis。

【适用方向】

源站学科分类标注为 Hematology、Biological Sciences、Genetics、Immunology、Evolutionary Biology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/SNPs_Array_Karyotyping_Reveals_a_Novel_Recurrent_20p13_Amplification_in_Primary_Myelofibrosis/131443

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Visani, Giuseppe; Rosaria Sapienza, Maria; Isidori, Alessandro; Tripodo, Claudio; Antonella Laginestra, Maria; Righi, Simona; et al. (2016). SNPs Array Karyotyping Reveals a Novel Recurrent 20p13 Amplification in Primary Myelofibrosis. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。