骨髓增生异常综合征中地西他滨耐药机制研究数据集

资源简介

骨髓增生异常综合征中地西他滨耐药机制研究数据集

【数据集背景】

本数据集源站标题为《Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome》。配套论文《Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome》发表于 PLoS ONE（2011），DOI：10.1371/journal.pone.0023372。源站首次发布：2011-08-17。

【数据内容】

源站原始描述：Purpose The DNA methylation inhibitor 5-aza-2′-deoxycytidine (DAC) is approved for the treatment of myelodysplastic syndromes (MDS), but resistance to DAC develops during treatment and mechanisms of resistance remain unknown. Therefore, we investigated mechanisms of primary and secondary resistance to DAC in MDS. Patients and Methods We performed Quantitative Real-Time PCR to examine expression of genes related to DAC metabolism prior to therapy in 32 responders and non-responders with MDS as we…

【数据结构与技术规格】

文件数 4 个，合计 171.01 KB。Table_S1.doc：application/msword，50.69 KB。Table_S2.doc：application/msword，45.06 KB。Table_S3.doc：application/msword，48.13 KB。数据集 DOI：10.1371/journal.pone.0023372。

【主题与分类】

源站学科分类：Molecular Biology、Hematology、Pharmacology。主题标签：mechanisms、decitabine、myelodysplastic。

【适用方向】

源站学科分类标注为 Molecular Biology、Hematology、Pharmacology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Mechanisms_of_Resistance_to_Decitabine_in_the_Myelodysplastic_Syndrome/134187

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Qin, Taichun; Castoro, Ryan; El Ahdab, Samih; Jelinek, Jaroslav; Wang, Xiaodan; Si, Jiali; et al. (2016). Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。